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Med17
Gene Detail
Symbol

Name
ID
Med17
mediator complex subunit 17
MGI:2182585
Synonyms
C330002H14Rik, Crsp6, Trap80
Feature Type
protein coding gene
Genetic Map
Chromosome 9
4.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:15260352-15279867 bp, - strand
From Ensembl annotation of GRCm38

  19516 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3151  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MED17
Gene Tree: Med17

Human
homologs
MED17, mediator complex subunit 17
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9440
neXtProt AC: NX_Q9NVC6

Human Synonyms: CRSP6, CRSP77, DRIP80, TRAP80

Human Chr (Location): 11q14; chr11:93784239-93813330 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human MED17

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Med17 interacts with 280 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (25)    Tissues (16)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 25
cDNA source data(82)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA MED17 ; Xenbase med17 ; ZFIN med17    NEW 
Molecular
reagents
All nucleic(82) cDNA(82)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000031935 (Evidence)
Entrez Gene 234959 (Evidence)
UniGene 44151
DFCI TC1575042, TC1715506
DoTS DT.101739542, DT.490347
NIA Mouse Gene Index U030496
Consensus CDS Project CCDS22834.1
International Mouse Phenotyping Consortium Status Med17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031935 Ensembl Gene Model | MGI Sequence Detail 19516 C57BL/6J ±  kb
transcript ENSMUST00000034411 Ensembl | MGI Sequence Detail 3899 Not Applicable 
polypeptide ENSMUSP00000034411 Ensembl | MGI Sequence Detail 649 Not Applicable 

For the selected sequences
All sequences(29) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(92 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019313 Mediator complex, subunit Med17
Protein Ontology PR:000010289 mediator of RNA polymerase II transcription subunit 17
References
(Earliest) J:76817 Ge K, et al., Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature. 2002 May 30;417(6888):563-7
(Latest) J:164442 Kagey MH, et al., Mediator and cohesin connect gene expression and chromatin architecture. Nature. 2010 Sep 23;467(7314):430-5
All references(40)
Other
accession IDs
MGI:2443890

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory