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Med17
Gene Detail
 Symbol
Name
ID
Med17
mediator complex subunit 17
MGI:2182585
Synonyms C330002H14Rik, Crsp6, Trap80
Feature Type protein coding gene
Genetic Map
Chromosome 9
4.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:15260352-15279867 bp, - strand
From Ensembl annotation of GRCm38

  19516 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3151  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Med17

Human
homologs
Human Homolog MED17, mediator complex subunit 17
NCBI Gene ID 9440
neXtProt AC  NX_Q9NVC6
Human Synonyms  CRSP6, CRSP77, DRIP80, TRAP80
Human Chr (Location)  11q14; chr11:93784239-93813330 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human MED17
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Med17 interacts with 281 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process androgen receptor signaling pathway, intracellular steroid hormone receptor signaling pathway, ...
Component mediator complex, membrane, ...
Function receptor activity, RNA polymerase II transcription cofactor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (25)    Tissues (16)    Images (2)
Theiler Stages: 17, 23
Assay TypeResults
RNA in situ 25
cDNA source data(82)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(82) cDNA(82)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000031935 (Evidence)
Entrez Gene234959 (Evidence)
UniGene44151
DFCITC1575042, TC1715506
DoTSDT.101739542, DT.490347
NIA Mouse Gene IndexU030496
Consensus CDS ProjectCCDS22834.1
International Mouse Knockout Project StatusMed17
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031935 Ensembl Gene Model | MGI Sequence Detail 19516 C57BL/6J ±  kb
transcript ENSMUST00000034411 Ensembl | MGI Sequence Detail 3899 Not Applicable 
polypeptide ENSMUSP00000034411 Ensembl | MGI Sequence Detail 649 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(6) UniProt(1)
Polymorphisms SNPs within 2kb(92 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR019313 Mediator complex, subunit Med17
Protein Ontology PR:000010289 mediator of RNA polymerase II transcription subunit 17
References (Earliest) J:76817 Ge K, et al., Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature. 2002 May 30;417(6888):563-7
(Latest) J:164442 Kagey MH, et al., Mediator and cohesin connect gene expression and chromatin architecture. Nature. 2010 Sep 23;467(7314):430-5
All references(39)
Other
accession IDs
MGI:2443890

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory