Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED14
  • Mouse genes Med14
  • Rat genes Med14
  • Zfish genes med14
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MED14	IPI	UniProtKB:Q71SY5	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED14	IPI	UniProtKB:Q96RN5	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED14	IPI	UniProtKB:Q9ULK4	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED14	IPI	UniProtKB:Q9Y2X0	Human	PMID:24882805
Molecular Function	GO:0005515	protein binding	MED14	IPI	UniProtKB:Q9ULK4	Human	PMID:25281560
Molecular Function	GO:0005515	protein binding	MED14	IPI	UniProtKB:Q71SY5	Human	PMID:25792360
Molecular Function	GO:0003713	transcription coactivator activity	MED14	IDA		Human	PMID:12037571
Molecular Function	GO:0003713	transcription coactivator activity	MED14	IDA		Human	PMID:12218053
Molecular Function	GO:0003712	transcription coregulator activity	MED14	IDA		Human	PMID:10198638
Cellular Component	GO:0070847	core mediator complex	MED14	IPI		Human	PMID:24882805
Cellular Component	GO:0016592	mediator complex	MED14	IDA		Human	PMID:10198638
Cellular Component	GO:0016592	mediator complex	MED14	IDA		Human	PMID:12037571
Cellular Component	GO:0016592	mediator complex	Med14	IDA		Mouse	PMID:15340084
Cellular Component	GO:0016020	membrane	MED14	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	MED14	IDA		Human	PMID:10235267
Cellular Component	GO:0005634	nucleus	MED14	IDA		Human	PMID:24882805
Biological Process	GO:0048514	blood vessel morphogenesis	med14	IMP	ZFIN:ZDB-GENO-080318-20	Zfish	PMID:17531218
Biological Process	GO:0007420	brain development	med14	IMP	ZFIN:ZDB-GENO-980202-175	Zfish	PMID:9007241
Biological Process	GO:0007420	brain development	med14	IMP	ZFIN:ZDB-GENO-980202-196	Zfish	PMID:9007241
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	med14	IMP	ZFIN:ZDB-GENO-150828-2	Zfish	PMID:26553192
Biological Process	GO:0014033	neural crest cell differentiation	med14	IMP	ZFIN:ZDB-GENO-150828-2	Zfish	PMID:26553192
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MED14	IDA		Human	PMID:10198638
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MED14	IDA		Human	PMID:12037571
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	MED14	IDA		Human	PMID:12218053
Biological Process	GO:0033081	regulation of T cell differentiation in thymus	med14	IMP	ZFIN:ZDB-MRPHLNO-230207-2	Zfish	PMID:35967429
Biological Process	GO:0035019	somatic stem cell population maintenance	Med14	IMP		Mouse	PMID:20720539
Biological Process	GO:0019827	stem cell population maintenance	med14	IMP	ZFIN:ZDB-GENO-150714-6	Zfish	PMID:25772472
Biological Process	GO:0021591	ventricular system development	med14	IMP	ZFIN:ZDB-GENO-120302-1	Zfish	PMID:9007238
Biological Process	GO:0021591	ventricular system development	med14	IMP	ZFIN:ZDB-GENO-980202-196	Zfish	PMID:9007241
Biological Process	GO:0021591	ventricular system development	med14	IMP	ZFIN:ZDB-GENO-980202-175	Zfish	PMID:9007241

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern