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Med14
Gene Detail
 Symbol
Name
ID
Med14
mediator complex subunit 14
MGI:1349442
Synonyms 9930001L01Rik, Crsp2, ENSMUSG00000073278, LOC270579, ORF1, Trap170
Feature Type protein coding gene
Genetic Map
Chromosome X
7.52 cM
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
ChrX:12675369-12762073 bp, - strand
From VEGA annotation of GRCm38

  86705 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22082  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Med14

Human
homologs
Human Homolog MED14, mediator complex subunit 14
NCBI Gene ID 9282
neXtProt AC  NX_O60244
Human Synonyms  CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, RGR1, TRAP170
Human Chr (Location)  Xp11.4; chrX:40649543-40736122 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(2) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Male chimeras hemizygous for a gene trapped allele appear normal at E10.5.
 
Phenotype Images(6)
Interactions
Med14 interacts with 427 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process androgen receptor signaling pathway, intracellular steroid hormone receptor signaling pathway, ...
Component mediator complex, membrane, ...
Function receptor activity, RNA polymerase II transcription cofactor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (232)    Tissues (153)    Images (47)
Theiler Stages: 16, 17, 21, 22, 23, 27
Assay TypeResults
RNA in situ 232
cDNA source data(19)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) Genomic(1) cDNA(19) Primer pair(1)
Microarray probesets(7)
Other database
links
VEGA Gene ModelOTTMUSG00000016997 (Evidence)
Ensembl Gene ModelENSMUSG00000064127 (Evidence)
Entrez Gene26896 (Evidence)
NIA Mouse Gene IndexU039271, U163087
Consensus CDS ProjectCCDS40874.1
International Mouse Knockout Project StatusMed14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016997 VEGA Gene Model | MGI Sequence Detail 86705 C57BL/6J ±  kb
transcript OTTMUST00000041216 VEGA | MGI Sequence Detail 6963 Not Applicable 
polypeptide OTTMUSP00000018469 VEGA | MGI Sequence Detail 1459 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(8) UniProt(4)
Polymorphisms RFLP(2) : SNPs within 2kb(278 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013947 Mediator complex, subunit Med14
Protein Ontology PR:000010286 mediator of RNA polymerase II transcription subunit 14
References (Earliest) J:58086 Takada S, et al., Detection and cloning of an X-linked locus associated with a NotI site that is not methylated on mouse inactivated X chromosome by the RLGS-M method. Genomics. 1999 Oct 1;61(1):92-100
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(43)
Other
accession IDs
MGI:2147974, MGI:2685487, MGI:3641973

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory