Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MED13
  • Mouse genes Med13
  • Rat genes Med13
  • Zfish genes med13a,med13b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Med13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	MED13	IDA		Human	PMID:10198638
Molecular Function	GO:0003713	transcription coactivator activity	MED13	IDA		Human	PMID:12037571
Molecular Function	GO:0003713	transcription coactivator activity	MED13	IDA		Human	PMID:12218053
Molecular Function	GO:0003712	transcription coregulator activity	MED13	IDA		Human	PMID:10198638
Cellular Component	GO:0016592	mediator complex	MED13	IDA		Human	PMID:10198638
Cellular Component	GO:0016592	mediator complex	MED13	IDA		Human	PMID:12037571
Cellular Component	GO:0016592	mediator complex	Med13	IDA		Mouse	PMID:15340084
Cellular Component	GO:0016020	membrane	MED13	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	MED13	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MED13	IDA		Human	PMID:10235267
Cellular Component	GO:0005634	nucleus	Med13	IDA		Rat	PMID:25287062|RGD:9681715
Biological Process	GO:0042632	cholesterol homeostasis	Med13	IDA		Mouse	MGI:MGI:5431176|PMID:22541436
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Med13	IDA		Mouse	MGI:MGI:5431176|PMID:22541436
Biological Process	GO:0001755	neural crest cell migration	med13b	IMP	ZFIN:ZDB-MRPHLNO-161013-2	Zfish	PMID:25137640
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	MED13	IDA		Human	PMID:10198638
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MED13	IDA		Human	PMID:12037571
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	MED13	IDA		Human	PMID:12218053
Biological Process	GO:0070328	triglyceride homeostasis	Med13	IDA		Mouse	MGI:MGI:5431176|PMID:22541436

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern