Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MC3R
  • Mouse genes Mc3r
  • Rat genes Mc3r
  • Zfish genes mc3r
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mc3r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004977	melanocortin receptor activity	Mc3r	IDA		Rat	PMID:17023527|RGD:1600765
Molecular Function	GO:0004977	melanocortin receptor activity	Mc3r	IMP		Rat	PMID:17023527|RGD:1600765
Molecular Function	GO:0004980	melanocyte-stimulating hormone receptor activity	MC3R	IPI	UniProtKB:P01189	Human	PMID:19743876
Molecular Function	GO:0004980	melanocyte-stimulating hormone receptor activity	Mc3r	IDA		Mouse	PMID:9454589
Molecular Function	GO:0042923	neuropeptide binding	MC3R	IMP		Human	PMID:15927146
Molecular Function	GO:0017046	peptide hormone binding	Mc3r	IDA		Rat	PMID:17023527|RGD:1600765
Molecular Function	GO:0017046	peptide hormone binding	Mc3r	IMP		Rat	PMID:17023527|RGD:1600765
Molecular Function	GO:0005515	protein binding	MC3R	IPI	UniProtKB:Q8TCY5	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MC3R	IPI	UniProtKB:Q96G30	Human	PMID:19329486
Molecular Function	GO:0005515	protein binding	MC3R	IPI	UniProtKB:P01189	Human	PMID:19743876
Molecular Function	GO:0005515	protein binding	Mc3r	IPI	PR:Q03288	Mouse	PMID:9454589
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	MC3R	IDA		Human	PMID:19329486
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	MC3R	IDA		Human	PMID:19743876
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Mc3r	IDA		Rat	PMID:15985309|RGD:1625180
Biological Process	GO:0032922	circadian regulation of gene expression	Mc3r	IMP		Mouse	MGI:MGI:3821632|PMID:19036988
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Mc3r	IDA		Mouse	MGI:MGI:1195529|PMID:9454589
Biological Process	GO:0042309	homoiothermy	Mc3r	IMP		Rat	PMID:21091037|RGD:6484594
Biological Process	GO:0045475	locomotor rhythm	Mc3r	IMP		Mouse	MGI:MGI:3821632|PMID:19036988
Biological Process	GO:0008217	regulation of blood pressure	Mc3r	IMP		Rat	PMID:21091037|RGD:6484594
Biological Process	GO:0060259	regulation of feeding behavior	Mc3r	IMP		Mouse	MGI:MGI:3821632|PMID:19036988
Biological Process	GO:0002027	regulation of heart rate	Mc3r	IMP		Rat	PMID:21091037|RGD:6484594
Biological Process	GO:0055078	sodium ion homeostasis	Mc3r	IEP		Rat	PMID:19570553|RGD:6484660

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern