Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MASTL
  • Mouse genes Mastl
  • Rat genes Mastl
  • Zfish genes mastl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mastl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016301	kinase activity	MASTL	IDA		Human	PMID:20818157
Molecular Function	GO:0005515	protein binding	Mastl	IPI	UniProtKB:Q924N4	Mouse	MGI:MGI:6221361|PMID:27782176
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MASTL	IDA		Human	PMID:20538976
Cellular Component	GO:0005813	centrosome	MASTL	IDA		Human	PMID:20538976
Cellular Component	GO:0032154	cleavage furrow	MASTL	IDA		Human	PMID:20538976
Cellular Component	GO:0032154	cleavage furrow	MASTL	IDA		Human	PMID:20818157
Cellular Component	GO:0005654	nucleoplasm	MASTL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MASTL	IDA		Human	PMID:20538976
Cellular Component	GO:0005634	nucleus	MASTL	IDA		Human	PMID:20818157
Biological Process	GO:0007147	female meiosis II	Mastl	IMP		Mouse	PMID:25246615
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	MASTL	IMP		Human	PMID:20538976
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	MASTL	IMP		Human	PMID:20818157
Biological Process	GO:0000278	mitotic cell cycle	MASTL	IMP		Human	PMID:20538976
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	MASTL	IMP		Human	PMID:20538976
Biological Process	GO:1904668	positive regulation of ubiquitin protein ligase activity	Mastl	IMP		Mouse	PMID:25246615
Biological Process	GO:0051726	regulation of cell cycle	MASTL	IMP		Human	PMID:20818157
Biological Process	GO:0002574	thrombocyte differentiation	mastl	IMP	ZFIN:ZDB-MRPHLNO-091002-1	Zfish	PMID:19460416
Biological Process	GO:0002574	thrombocyte differentiation	mastl	IMP	ZFIN:ZDB-MRPHLNO-091002-2	Zfish	PMID:19460416

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern