Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARCKSL1
  • Mouse genes Marcksl1
  • Rat genes Marcksl1
  • Zfish genes marcksl1a,marcksl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Marcksl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	MARCKSL1	IPI	UniProtKB:Q9Y4K0	Human	PMID:24863880
Cellular Component	GO:0070062	extracellular exosome	MARCKSL1	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	MARCKSL1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0099523	presynaptic cytosol	Marcksl1	IDA		Rat	PMID:8557647|RGD:13702350
Cellular Component	GO:0042734	presynaptic membrane	Marcksl1	IDA		Rat	PMID:8557647|RGD:13702350
Cellular Component	GO:0008021	synaptic vesicle	Marcksl1	IDA		Rat	PMID:8557647|RGD:13702350
Biological Process	GO:0072554	blood vessel lumenization	marcksl1b	IMP	ZFIN:ZDB-GENO-220706-7	Zfish	PMID:33127887
Biological Process	GO:0072554	blood vessel lumenization	marcksl1a	IMP	ZFIN:ZDB-GENO-220706-6	Zfish	PMID:33127887
Biological Process	GO:0051216	cartilage development	marcksl1a	IMP	ZFIN:ZDB-MRPHLNO-180720-3	Zfish	PMID:27554589
Biological Process	GO:0051216	cartilage development	marcksl1b	IMP	ZFIN:ZDB-MRPHLNO-180720-2	Zfish	PMID:27554589
Biological Process	GO:0008283	cell population proliferation	Marcksl1	IDA		Mouse	PMID:17688421
Biological Process	GO:0007417	central nervous system development	marcksl1a	IMP	ZFIN:ZDB-MRPHLNO-180720-3	Zfish	PMID:27554589
Biological Process	GO:0007417	central nervous system development	marcksl1b	IMP	ZFIN:ZDB-MRPHLNO-180720-2	Zfish	PMID:27554589
Biological Process	GO:0003407	neural retina development	marcksl1a	IMP	ZFIN:ZDB-MRPHLNO-180720-3	Zfish	PMID:27554589
Biological Process	GO:0003407	neural retina development	marcksl1b	IMP	ZFIN:ZDB-MRPHLNO-180720-2	Zfish	PMID:27554589
Biological Process	GO:0008284	positive regulation of cell population proliferation	Marcksl1	IDA		Mouse	PMID:17688421
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Marcksl1	IDA		Rat	PMID:16987251|RGD:13792524
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Marcksl1	IEP		Rat	PMID:16987251|RGD:13792524
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Marcksl1	IMP		Rat	PMID:16987251|RGD:13792524

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern