Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MARCHF1
  • Mouse genes Marchf1
  • Rat genes Marchf1
  • Zfish genes marchf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Marchf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042287	MHC protein binding	MARCHF1	IDA		Human	PMID:18389477
Molecular Function	GO:0061630	ubiquitin protein ligase activity	MARCHF1	IDA		Human	PMID:14722266
Molecular Function	GO:0061630	ubiquitin protein ligase activity	MARCHF1	IDA		Human	PMID:18305173
Molecular Function	GO:0061630	ubiquitin protein ligase activity	MARCHF1	IDA		Human	PMID:18389477
Molecular Function	GO:0061630	ubiquitin protein ligase activity	MARCHF1	IDA		Human	PMID:19117940
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Marchf1	IDA		Mouse	PMID:17255932
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Marchf1	IDA		Mouse	MGI:MGI:3703462|PMID:17255932
Cellular Component	GO:0031901	early endosome membrane	MARCHF1	IDA		Human	PMID:19117940
Cellular Component	GO:0031901	early endosome membrane	Marchf1	IDA		Mouse	MGI:MGI:4430128|PMID:19880452
Cellular Component	GO:0005783	endoplasmic reticulum	MARCHF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Marchf1	IDA		Mouse	MGI:MGI:4430128|PMID:19880452
Cellular Component	GO:0005768	endosome	MARCHF1	IDA		Human	PMID:14722266
Cellular Component	GO:0005794	Golgi apparatus	MARCHF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MARCHF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031902	late endosome membrane	MARCHF1	IDA		Human	PMID:19117940
Cellular Component	GO:0031902	late endosome membrane	Marchf1	IDA		Mouse	MGI:MGI:4430128|PMID:19880452
Cellular Component	GO:0005765	lysosomal membrane	Marchf1	IDA		Mouse	MGI:MGI:4430128|PMID:19880452
Cellular Component	GO:0005764	lysosome	MARCHF1	IDA		Human	PMID:14722266
Cellular Component	GO:0005886	plasma membrane	MARCHF1	IDA		Human	PMID:19117940
Cellular Component	GO:0032588	trans-Golgi network membrane	Marchf1	IDA		Mouse	MGI:MGI:4430128|PMID:19880452
Biological Process	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	MARCHF1	IDA		Human	PMID:18389477
Biological Process	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	Marchf1	IMP		Mouse	MGI:MGI:3703462|PMID:17255932
Biological Process	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	Marchf1	IMP		Mouse	MGI:MGI:4430994|PMID:19917682
Biological Process	GO:0006955	immune response	MARCHF1	IDA		Human	PMID:18305173
Biological Process	GO:0006955	immune response	MARCHF1	IDA		Human	PMID:18389477
Biological Process	GO:0006955	immune response	Marchf1	IDA		Mouse	MGI:MGI:3703462|PMID:17255932
Biological Process	GO:0006955	immune response	Marchf1	IDA		Mouse	MGI:MGI:4430994|PMID:19917682
Biological Process	GO:0000209	protein polyubiquitination	MARCHF1	IDA		Human	PMID:19117940
Biological Process	GO:0000209	protein polyubiquitination	MARCHF1	IMP		Human	PMID:27577745
Biological Process	GO:0000209	protein polyubiquitination	Marchf1	IDA		Mouse	MGI:MGI:3703462|PMID:17255932

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern