Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAPK11
  • Mouse genes Mapk11
  • Rat genes Mapk11
  • Zfish genes mapk11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Mapk11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Mapk11	IDA		Rat	PMID:16879317|RGD:2298806
Molecular Function	GO:0004707	MAP kinase activity	MAPK11	IDA		Human	PMID:10330143
Molecular Function	GO:0004707	MAP kinase activity	MAPK11	IDA		Human	PMID:8663524
Molecular Function	GO:0004707	MAP kinase activity	Mapk11	IMP		Mouse	PMID:20551513
Molecular Function	GO:0004707	MAP kinase activity	Mapk11	IDA		Rat	PMID:16879317|RGD:2298806
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:P04637	Human	PMID:17254968
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:O43257	Human	PMID:17380123
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q16644	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q16644	Human	PMID:23602568
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q16644	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q16644	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:O14908-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:P02489	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:P17252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q13153	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q14204	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q16637	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q86V38	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	MAPK11	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Mapk11	IPI	UniProtKB:P47811	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAPK11	IDA		Human	PMID:35857590
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Mapk11	EXP		Mouse	MGI:MGI:4887337|PMID:16364914
Cellular Component	GO:0005829	cytosol	Mapk11	IMP		Mouse	PMID:20551513
Biological Process	GO:0060348	bone development	Mapk11	IMP	MGI:MGI:3696052	Mouse	PMID:20551513
Biological Process	GO:0060038	cardiac muscle cell proliferation	Mapk11	IMP	MGI:MGI:3609429	Mouse	PMID:21768366
Biological Process	GO:0071347	cellular response to interleukin-1	MAPK11	IDA		Human	PMID:8663524
Biological Process	GO:0071493	cellular response to UV-B	MAPK11	IDA		Human	PMID:35857590
Biological Process	GO:0098586	cellular response to virus	MAPK11	IMP		Human	PMID:25754930
Biological Process	GO:0000165	MAPK cascade	Mapk11	IMP		Mouse	PMID:20551513
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	Mapk11	IMP	MGI:MGI:3609429	Mouse	PMID:21768366
Biological Process	GO:0001649	osteoblast differentiation	Mapk11	IMP		Mouse	PMID:20551513
Biological Process	GO:0010628	positive regulation of gene expression	MAPK11	IMP		Human	PMID:25754930
Biological Process	GO:0032735	positive regulation of interleukin-12 production	MAPK11	IMP		Human	PMID:25754930
Biological Process	GO:0006468	protein phosphorylation	Mapk11	IDA		Rat	PMID:16879317|RGD:2298806
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	Mapk11	IGI	MGI:MGI:1346865	Mouse	PMID:21768366
Biological Process	GO:0051403	stress-activated MAPK cascade	MAPK11	IDA		Human	PMID:35857590
Biological Process	GO:0051403	stress-activated MAPK cascade	MAPK11	IDA		Human	PMID:8663524
Biological Process	GO:0031098	stress-activated protein kinase signaling cascade	MAPK11	IDA		Human	PMID:35857590

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern