Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAP3K13
  • Mouse genes Map3k13
  • Rat genes Map3k13
  • Zfish genes si:ch211-45c16.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Map3k13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	MAP3K13	IPI	UniProtKB:P30048	Human	PMID:12492477
Molecular Function	GO:0042802	identical protein binding	MAP3K13	IPI	UniProtKB:O43283	Human	PMID:11163770
Molecular Function	GO:0106137	IkappaB kinase complex binding	MAP3K13	IDA		Human	PMID:12492477
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	MAP3K13	IDA		Human	PMID:11726277
Molecular Function	GO:0005515	protein binding	MAP3K13	IPI	UniProtKB:Q9UQF2	Human	PMID:11726277
Molecular Function	GO:0005515	protein binding	MAP3K13	IPI	UniProtKB:O14920	Human	PMID:12492477
Molecular Function	GO:0042803	protein homodimerization activity	MAP3K13	IDA		Human	PMID:11163770
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Molecular Function	GO:0004674	protein serine/threonine kinase activity	MAP3K13	IDA		Human	PMID:9353328
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Cellular Component	GO:0016020	membrane	MAP3K13	IDA		Human	PMID:9353328
Biological Process	GO:0007254	JNK cascade	MAP3K13	IDA		Human	PMID:11726277
Biological Process	GO:0007254	JNK cascade	MAP3K13	IDA		Human	PMID:9353328
Biological Process	GO:0007254	JNK cascade	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0045773	positive regulation of axon extension	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:1905492	positive regulation of branching morphogenesis of a nerve	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0014042	positive regulation of neuron maturation	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0150012	positive regulation of neuron projection arborization	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	MAP3K13	IDA		Human	PMID:12492477
Biological Process	GO:0045860	positive regulation of protein kinase activity	Map3k13	IMP		Mouse	MGI:MGI:5810221|PMID:27511108
Biological Process	GO:0046777	protein autophosphorylation	MAP3K13	IDA		Human	PMID:9353328
Biological Process	GO:0006468	protein phosphorylation	MAP3K13	IDA		Human	PMID:11726277
Biological Process	GO:0006468	protein phosphorylation	MAP3K13	IDA		Human	PMID:9353328
Biological Process	GO:0051403	stress-activated MAPK cascade	MAP3K13	IDA		Human	PMID:11726277

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern