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Map3k13 Gene Detail
Summary
  • Symbol
    Map3k13
  • Name
    mitogen-activated protein kinase kinase kinase 13
  • Synonyms
    C130026N12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444243
    NCBI Gene: 71751
  • Gene Overview
    MyGene.info: MAP3K13
Location & Maps
more
  • Sequence Map
    Chr16:21891969-21931877 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      39909 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 12.92 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MAP3K13, mitogen-activated protein kinase kinase kinase 13
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MAP3K13, mitogen-activated protein kinase kinase kinase 13
    Orthology source: HGNC, HomoloGene
  • Synonyms
    LZK, MEKK13, MLK
  • Links
    NCBI Gene ID: 9175
    neXtProt AC: NX_O43283

  • Chr Location
    3q27; chr3:185282941-185489094 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033618 Ensembl Gene Model | MGI Sequence Detail 39909 C57BL/6J ±  kb
transcript ENSMUST00000042065 Ensembl | MGI Sequence Detail 6709 Not Applicable  
polypeptide ENSMUSP00000047388 Ensembl | MGI Sequence Detail 959 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    581 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010132 mitogen-activated protein kinase kinase kinase 13
  • EC
  • InterPro Domains
    IPR017419 Mitogen-activated protein kinase kinase kinase 12/13
    IPR027258 Mitogen-activated protein kinase kinase kinase 13
    IPR000719 Protein kinase domain
    IPR011009 Protein kinase-like domain
    IPR008271 Serine/threonine-protein kinase, active site
    IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
Molecular
Reagents
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  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 19
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory