Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAN2B1
  • Mouse genes Man2b1
  • Rat genes Man2b1
  • Zfish genes man2b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Man2b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004559	alpha-mannosidase activity	Man2b1	IDA		Mouse	PMID:9305783
Molecular Function	GO:0004559	alpha-mannosidase activity	Man2b1	IMP	MGI:MGI:3584185	Mouse	PMID:10400983
Molecular Function	GO:0004559	alpha-mannosidase activity	Man2b1	IDA		Mouse	PMID:9355733
Molecular Function	GO:0004559	alpha-mannosidase activity	Man2b1	IDA		Rat	PMID:8702598|RGD:1625498
Molecular Function	GO:0004559	alpha-mannosidase activity	Man2b1	IMP		Rat	PMID:8717430|RGD:1625507
Molecular Function	GO:0005537	mannose binding	Man2b1	IDA		Rat	PMID:8702598|RGD:1625498
Cellular Component	GO:0070062	extracellular exosome	MAN2B1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	MAN2B1	IDA		Human	PMID:25645918
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MAN2B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043202	lysosomal lumen	Man2b1	IDA		Mouse	PMID:9305783
Cellular Component	GO:0005764	lysosome	Man2b1	IDA		Rat	PMID:8702598|RGD:1625498
Cellular Component	GO:0005654	nucleoplasm	MAN2B1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007611	learning or memory	Man2b1	IMP	MGI:MGI:3584185	Mouse	PMID:16014715
Biological Process	GO:0006013	mannose metabolic process	Man2b1	IDA		Mouse	PMID:9305783
Biological Process	GO:0006013	mannose metabolic process	Man2b1	IMP	MGI:MGI:3584185	Mouse	PMID:10400983
Biological Process	GO:0006013	mannose metabolic process	Man2b1	IDA		Mouse	PMID:9355733
Biological Process	GO:0009313	oligosaccharide catabolic process	Man2b1	IDA		Mouse	PMID:9305783
Biological Process	GO:0036211	protein modification process	MAN2B1	IDA		Human	PMID:8910458

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern