Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes MAFF
  • Mouse genes Maff
  • Rat genes Maff
  • Zfish genes maff
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Maff

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	maff	IDA		Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	maff	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0003677	DNA binding	maff	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	MAFF	IDA		Human	PMID:12490281
Molecular Function	GO:0003700	DNA-binding transcription factor activity	maff	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:O14867	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:O15525	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:P18847	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q14494	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q16236	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q16649	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q8N1L9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q9BYV9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q9NR55	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q9Y4A8	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:O14867	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:O14867	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q9BYV9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q9Y4A8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	MAFF	IPI	UniProtKB:Q14494:PRO_0000443103	Human	PMID:8932385
Molecular Function	GO:0046982	protein heterodimerization activity	maff	IPI	UniProtKB:Q7ZVI2	Zfish	PMID:15207702
Molecular Function	GO:0046982	protein heterodimerization activity	maff	IPI	UniProtKB:Q7ZZR2	Zfish	PMID:15207702
Molecular Function	GO:0043565	sequence-specific DNA binding	MAFF	IDA		Human	PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	MAFF	IDA		Human	PMID:28473536
Cellular Component	GO:0005739	mitochondrion	MAFF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	MAFF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	MAFF	IPI		Human	PMID:23661758
Cellular Component	GO:0005667	transcription regulator complex	maff	IDA		Zfish	PMID:15207702
Biological Process	GO:0001701	in utero embryonic development	Maff	IGI	MGI:MGI:96911	Mouse	PMID:15087497
Biological Process	GO:0001701	in utero embryonic development	Maff	IGI	MGI:MGI:1858732	Mouse	PMID:15087497
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	maff	IGI	ZFIN:ZDB-GENE-030723-2	Zfish	PMID:15207702
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	MAFF	IDA		Human	PMID:12490281
Biological Process	GO:0045604	regulation of epidermal cell differentiation	Maff	IGI	MGI:MGI:96911	Mouse	PMID:15087497
Biological Process	GO:0045604	regulation of epidermal cell differentiation	Maff	IGI	MGI:MGI:1858732	Mouse	PMID:15087497
Biological Process	GO:0035914	skeletal muscle cell differentiation	Maff	IMP		Mouse	PMID:22147266

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern