About   Help   FAQ
Maff Gene Detail
Summary
  • Symbol
    Maff
  • Name
    v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
  • Feature Type
    protein coding gene
  • IDs
    MGI:96910
    NCBI Gene: 17133
  • Gene Overview
    MyGene.info: MAFF
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:79230821-79243276 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    47 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96910
 protein coding gene Chr15:79230821-79243278 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022072
 protein coding gene Chr15:79607216-79620671 (+)
A/J MGP_AJ_G0022033
 protein coding gene Chr15:76866393-76877910 (+)
AKR/J MGP_AKRJ_G0022008
 protein coding gene Chr15:79011062-79022578 (+)
BALB/cJ MGP_BALBcJ_G0022039
 protein coding gene Chr15:76858704-76870264 (+)
C3H/HeJ MGP_C3HHeJ_G0021810
 protein coding gene Chr15:79006077-79018008 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022482
 protein coding gene Chr15:82759020-82771623 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020012
 protein coding gene Chr15:73347718-73359115 (+)
CAST/EiJ MGP_CASTEiJ_G0021331
 protein coding gene Chr15:79707804-79720498 (+)
CBA/J MGP_CBAJ_G0021775
 protein coding gene Chr15:85319561-85331066 (+)
DBA/2J MGP_DBA2J_G0021904
 protein coding gene Chr15:76349098-76360663 (+)
FVB/NJ MGP_FVBNJ_G0021882
 protein coding gene Chr15:75380175-75392114 (+)
LP/J MGP_LPJ_G0021972
 protein coding gene Chr15:79799154-79810675 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021902
 protein coding gene Chr15:90441923-90456466 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022496
 protein coding gene Chr15:79024832-79036391 (+)
PWK/PhJ MGP_PWKPhJ_G0021073
 protein coding gene Chr15:76357839-76369608 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020910
 protein coding gene Chr15:78833901-78847536 (+)
WSB/EiJ MGP_WSBEiJ_G0021383
 protein coding gene Chr15:79408703-79420258 (+)



Homology
more
  • Human Ortholog
    MAFF, MAF bZIP transcription factor F
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAFF, MAF bZIP transcription factor F
  • Synonyms
    hMafF, U-MAF
  • Links
    NCBI Gene ID: 23764
    neXtProt AC: NX_Q9ULX9
    UniProt: Q9ULX9

  • Chr Location
    22q13.1; chr22:38201932-38216511 (+)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    31 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    2
  • Targeted
    5
  • Genomic Mutations
    3 involving Maff
  • Find Mice (IMSR)
    8 strains or lines available
Homozygous null mice are viable and fertile and show no obvious functional deficiencies.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    811
  • Tissues
    172
  • cDNA Data
    24
  • Literature Summary
    10
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042622 Ensembl Gene Model | MGI Sequence Detail 12456 C57BL/6J ±  kb
transcript ENSMUST00000229130 Ensembl | MGI Sequence Detail 1873 Not Applicable  
polypeptide ENSMUSP00000154850 Ensembl | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 1
    cDNA 24
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-12102
References
more
  • Summaries
    All 63
    Developmental Gene Expression 10
    Diseases 1
    Gene Ontology 6
    Phenotypes 31
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
09/14/2021
MGI 6.17 		The Jackson Laboratory