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Maff Gene Detail
Summary
  • Symbol
    Maff
  • Name
    v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
  • Feature Type
    protein coding gene
  • IDs
    MGI:96910
    NCBI Gene: 17133
  • Gene Overview
    MyGene.info: MAFF
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr15:79346621-79359076 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      12456 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 37.70 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    MAFF, MAF bZIP transcription factor F
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MAFF, MAF bZIP transcription factor F
    Orthology source: HGNC, HomoloGene
  • Synonyms
    hMafF, U-MAF
  • Links
    NCBI Gene ID: 23764
    neXtProt AC: NX_Q9ULX9
    UniProt: Q9ULX9

  • Chr Location
    22q13.1; chr22:38201932-38216511 (+)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 1 genetic background
    30 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    2
  • Targeted
    5
  • Genomic Mutations
    3 involving Maff
  • Find Mice (IMSR)
    5 strains or lines available
Homozygous null mice are viable and fertile and show no obvious functional deficiencies.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    179
  • Tissues
    172
  • cDNA Data
    24
  • Literature Summary
    8
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042622 Ensembl Gene Model | MGI Sequence Detail 12456 C57BL/6J ±  kb
transcript ENSMUST00000229130 Ensembl | MGI Sequence Detail 1873 Not Applicable  
polypeptide ENSMUSP00000154850 Ensembl | MGI Sequence Detail 156 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    51 from dbSNP Build 142
  • RFLP
    1
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    Genomic 1
    cDNA 24
    Primer pair 3

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-12102
References
more
  • Summaries
    All 60
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 6
    Phenotypes 30
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/11/2018
MGI 6.12 		The Jackson Laboratory