Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LZTFL1
  • Mouse genes Lztfl1
  • Rat genes Lztfl1
  • Zfish genes lztfl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lztfl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062063	BBSome binding	Lztfl1	IDA		Mouse	PMID:22072986
Molecular Function	GO:0042802	identical protein binding	LZTFL1	IPI	UniProtKB:Q9NQ48	Human	PMID:22072986
Molecular Function	GO:0042802	identical protein binding	LZTFL1	IPI	UniProtKB:Q9NQ48	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	LZTFL1	IPI	UniProtKB:Q9NQ48	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	LZTFL1	IPI	UniProtKB:Q9NQ48	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q3SYG4	Human	PMID:22072986
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q96HA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q3SYG4	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q3SYG4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:P20618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q6AZZ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q9H8S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q9HAT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LZTFL1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Lztfl1	IPI	PR:Q9D0P8	Mouse	PMID:34023333
Molecular Function	GO:0005515	protein binding	Lztfl1	IPI	PR:Q811G0	Mouse	PMID:22072986
Molecular Function	GO:0044877	protein-containing complex binding	LZTFL1	IDA		Human	PMID:24550735
Molecular Function	GO:0044877	protein-containing complex binding	Lztfl1	IDA		Mouse	MGI:MGI:5560383|PMID:24550735
Cellular Component	GO:0005929	cilium	Lztfl1	IDA		Mouse	PMID:34023333
Cellular Component	GO:0005737	cytoplasm	Lztfl1	IDA		Mouse	PMID:34023333
Cellular Component	GO:0005737	cytoplasm	Lztfl1	IPI	PR:Q9D0P8	Mouse	PMID:34023333
Cellular Component	GO:0005737	cytoplasm	lztfl1	IDA		Zfish	PMID:31293455
Cellular Component	GO:0005829	cytosol	LZTFL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0002177	manchette	Lztfl1	IDA		Mouse	PMID:34023333
Cellular Component	GO:0005634	nucleus	lztfl1	IDA		Zfish	PMID:31293455
Biological Process	GO:0030317	flagellated sperm motility	Lztfl1	IMP	MGI:MGI:4363232	Mouse	PMID:34023333
Biological Process	GO:1903568	negative regulation of protein localization to ciliary membrane	LZTFL1	IMP		Human	PMID:22072986
Biological Process	GO:1903565	negative regulation of protein localization to cilium	LZTFL1	IMP		Human	PMID:22072986
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	lztfl1	IDA		Zfish	PMID:31293455
Biological Process	GO:0007283	spermatogenesis	Lztfl1	IMP	MGI:MGI:4363232	Mouse	PMID:34023333

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern