Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYZ
  • Mouse genes Lyz2
  • Rat genes Lyz2
  • Zfish genes lyz
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lyz2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016798	hydrolase activity, acting on glycosyl bonds	Lyz2	IMP		Rat	PMID:2840982|RGD:1599862
Molecular Function	GO:0042802	identical protein binding	LYZ	IPI	UniProtKB:P61626	Human	PMID:23353684
Molecular Function	GO:0003796	lysozyme activity	Lyz2	IDA		Mouse	MGI:MGI:2654300|PMID:12411294
Molecular Function	GO:0003796	lysozyme activity	Lyz2	IDA		Rat	PMID:12965127|RGD:1599863
Molecular Function	GO:0003796	lysozyme activity	Lyz2	IMP		Rat	PMID:2840982|RGD:1599862
Cellular Component	GO:0005737	cytoplasm	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0070062	extracellular exosome	LYZ	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	LYZ	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	LYZ	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	LYZ	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	LYZ	IDA		Human	PMID:21805676
Cellular Component	GO:0005615	extracellular space	LYZ	HDA		Human	PMID:22664934
Cellular Component	GO:0005615	extracellular space	LYZ	HDA		Human	PMID:23580065
Cellular Component	GO:0000137	Golgi cis cisterna	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0005795	Golgi stack	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0005902	microvillus	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0048237	rough endoplasmic reticulum lumen	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0030141	secretory granule	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	Lyz2	IDA		Rat	PMID:9208328|RGD:1599861
Biological Process	GO:0048469	cell maturation	lyz	IMP		Zfish	PMID:27268086
Biological Process	GO:0042742	defense response to bacterium	LYZ	IDA		Human	PMID:21093056
Biological Process	GO:0042742	defense response to bacterium	Lyz2	IMP		Mouse	MGI:MGI:2654300|PMID:12411294
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Lyz2	IDA		Mouse	MGI:MGI:3042773|PMID:14977423
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Lyz2	IMP		Rat	PMID:2840982|RGD:1599862
Biological Process	GO:0050830	defense response to Gram-positive bacterium	LYZ	IDA		Human	PMID:21093056
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Lyz2	IDA		Mouse	MGI:MGI:3042773|PMID:14977423
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Lyz2	IMP		Rat	PMID:2840982|RGD:1599862
Biological Process	GO:0031640	killing of cells of another organism	LYZ	IDA		Human	PMID:9727055
Biological Process	GO:0001895	retina homeostasis	LYZ	HEP		Human	PMID:23580065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern