Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC4
  • Mouse genes Lrrc4
  • Rat genes Lrrc4
  • Zfish genes lrrc4.1,lrrc4.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRRC4	IPI	UniProtKB:Q96CW9	Human	PMID:21946559
Molecular Function	GO:0005515	protein binding	LRRC4	IPI	UniProtKB:Q9Y2I2	Human	PMID:21946559
Molecular Function	GO:0005515	protein binding	Lrrc4	IPI	PR:Q811D0	Mouse	PMID:16980967
Molecular Function	GO:0005515	protein binding	Lrrc4	IPI	PR:Q62108	Mouse	PMID:16980967
Molecular Function	GO:0005515	protein binding	Lrrc4	IPI	PR:Q8R4F1	Mouse	PMID:16980967
Molecular Function	GO:0005515	protein binding	Lrrc4	IPI	PR:Q91XM9	Mouse	PMID:16980967
Molecular Function	GO:0005515	protein binding	Lrrc4	IPI	PR:P70175	Mouse	PMID:16980967
Molecular Function	GO:0005515	protein binding	lrrc4.1	IPI	UniProtKB:A8BB75	Zfish	PMID:19765300
Cellular Component	GO:0043197	dendritic spine	Lrrc4	IDA		Mouse	PMID:16980967
Cellular Component	GO:0060076	excitatory synapse	Lrrc4	IDA		Mouse	PMID:16980967
Cellular Component	GO:0098978	glutamatergic synapse	Lrrc4	IMP		Mouse	PMID:25411505
Cellular Component	GO:0098978	glutamatergic synapse	Lrrc4	IDA		Mouse	PMID:25411505
Cellular Component	GO:0098978	glutamatergic synapse	Lrrc4	IDA		Rat	PMID:16980967|RGD:13702267
Cellular Component	GO:0044309	neuron spine	Lrrc4	IDA		Mouse	PMID:16980967
Cellular Component	GO:0098839	postsynaptic density membrane	Lrrc4	IDA		Mouse	PMID:25411505
Cellular Component	GO:0098839	postsynaptic density membrane	Lrrc4	IDA		Rat	PMID:16980967|RGD:13702267
Cellular Component	GO:0045211	postsynaptic membrane	Lrrc4	IDA		Mouse	PMID:16980967
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Lrrc4	IDA		Mouse	PMID:25411505
Cellular Component	GO:0045202	synapse	Lrrc4	IDA		Mouse	PMID:16980967
Biological Process	GO:1904861	excitatory synapse assembly	Lrrc4	IMP		Mouse	PMID:16980967
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Lrrc4	IDA		Mouse	PMID:25411505
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Lrrc4	IMP		Mouse	PMID:25411505
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	Lrrc4	IDA		Mouse	PMID:16980967
Biological Process	GO:0050808	synapse organization	Lrrc4	IDA		Mouse	PMID:16980967
Biological Process	GO:0099560	synaptic membrane adhesion	Lrrc4	IDA		Rat	PMID:16980967|RGD:13702267
Biological Process	GO:0099560	synaptic membrane adhesion	Lrrc4	IMP		Rat	PMID:16980967|RGD:13702267

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern