Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRC10
  • Mouse genes Lrrc10
  • Rat genes Lrrc10
  • Zfish genes lrrc10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrc10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Lrrc10	IDA		Mouse	PMID:23236519
Molecular Function	GO:0051393	alpha-actinin binding	Lrrc10	IDA		Mouse	PMID:23236519
Cellular Component	GO:0005856	cytoskeleton	Lrrc10	IDA		Mouse	PMID:15830381
Cellular Component	GO:0005739	mitochondrion	Lrrc10	IDA		Mouse	PMID:14751244
Cellular Component	GO:0030016	myofibril	Lrrc10	IDA		Mouse	PMID:18781631
Cellular Component	GO:0005634	nucleus	Lrrc10	IDA		Mouse	PMID:15830381
Cellular Component	GO:0005634	nucleus	Lrrc10	IDA		Mouse	PMID:14751244
Cellular Component	GO:0030017	sarcomere	Lrrc10	IDA		Mouse	PMID:23236519
Biological Process	GO:0055013	cardiac muscle cell development	Lrrc10	IMP	MGI:MGI:3809940	Mouse	PMID:23236519
Biological Process	GO:0061026	cardiac muscle tissue regeneration	lrrc10	IMP	ZFIN:ZDB-GENO-191219-17	Zfish	PMID:30462998
Biological Process	GO:0060047	heart contraction	lrrc10	IMP	ZFIN:ZDB-MRPHLNO-071119-1	Zfish	PMID:17601532
Biological Process	GO:0001947	heart looping	lrrc10	IMP	ZFIN:ZDB-MRPHLNO-071119-1	Zfish	PMID:17601532

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern