Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRBA
  • Mouse genes Lrba
  • Rat genes Lrba
  • Zfish genes im:7138144,lrba
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrba

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRBA	IPI	UniProtKB:O60784	Human	PMID:31263572
Cellular Component	GO:0031410	cytoplasmic vesicle	Lrba	IDA		Mouse	PMID:11254716
Cellular Component	GO:0005783	endoplasmic reticulum	Lrba	IDA		Mouse	MGI:MGI:1932145|PMID:11254716
Cellular Component	GO:0005764	lysosome	Lrba	IDA		Mouse	MGI:MGI:1932145|PMID:11254716
Cellular Component	GO:0016020	membrane	LRBA	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	Lrba	IDA		Mouse	MGI:MGI:1932145|PMID:11254716
Cellular Component	GO:0005802	trans-Golgi network	Lrba	IDA		Mouse	MGI:MGI:1932145|PMID:11254716
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Lrba	IEP		Mouse	PMID:20439489
Biological Process	GO:0000423	mitophagy	LRBA	IMP		Human	PMID:33773106
Biological Process	GO:0034497	protein localization to phagophore assembly site	LRBA	IMP		Human	PMID:33773106

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern