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Lrba
Gene Detail
 Symbol
Name
ID
Lrba
LPS-responsive beige-like anchor
MGI:1933162
Synonyms D3Ertd775e, Lba
Feature Type protein coding gene
Genetic Map
Chromosome 3
37.83 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr3:86224690-86782693 bp, + strand
From Ensembl annotation of GRCm38

  558004 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:36205  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Lrba

Human
homologs
Human Homolog LRBA, LPS-responsive vesicle trafficking, beach and anchor containing
NCBI Gene ID 987
neXtProt AC  NX_P50851
Human Synonyms  BGL, CDC4L, CVID8, LAB300, LBA
Human Chr (Location)  4q31.3; chr4:150264659-151015727 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human LRBA
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(10) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Lrba interacts with 297 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process endosomal transport, protein localization, ...
Component cell, cytoplasmic membrane-bounded vesicle, ...
Function protein kinase A binding
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (34)    Tissues (13)    Images (2)
Theiler Stages: 15, 17, 19, 23
Assay TypeResults
RNA in situ 34
cDNA source data(60)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(62) cDNA(60) Primer pair(2)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000028080 (Evidence)
Entrez Gene80877 (Evidence)
UniGene439825
DFCITC1580201, TC1594789, TC1619477, TC1662487, TC1669010
DoTSDT.40175962, DT.111052023, DT.487922, DT.532006, DT.94157660, DT.94199913, DT.97409719, DT.97409720
Consensus CDS ProjectCCDS38470.1
International Mouse Knockout Project StatusLrba
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028080 Ensembl Gene Model | MGI Sequence Detail 558004 C57BL/6J ±  kb
transcript ENSMUST00000107635 Ensembl | MGI Sequence Detail 9882 Not Applicable 
polypeptide ENSMUSP00000103261 Ensembl | MGI Sequence Detail 2854 Not Applicable 

For the selected sequences
All sequences(62) RefSeq(22) UniProt(5)
Polymorphisms SNPs within 2kb(2433 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2439)
Protein-related
information
ResourceIDDescription
InterPro IPR011989 Armadillo-like helical
InterPro IPR016024 Armadillo-type fold
InterPro IPR000409 BEACH domain
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR010508 Domain of unknown function DUF1088
InterPro IPR023362 PH-BEACH domain
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000009910 lipopolysaccharide-responsive and beige-like anchor protein
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(37)
Other
accession IDs
MGI:1289290, MGI:2140073

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory