Lrba Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lrba
LPS-responsive beige-like anchor
MGI:1933162

18 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lrba^{em1(IMPC)Wtsi}/Lrba^{em1(IMPC)Wtsi} C57BL/6N-Lrba^{em1(IMPC)Wtsi}/Wtsi	abnormal ear position	J:211773
	absent pinna reflex	J:211773
	decreased circulating chloride level	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating amylase level	J:211773
	increased circulating calcium level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating creatinine level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating total protein level	J:211773
Lrba^em1Btlr/Lrba^em1Btlr C57BL/6J-Lrba^em1Btlr	increased susceptibility to induced colitis	J:274652
Lrba^em2Btlr/Lrba^em2Btlr C57BL/6J-Lrba^em2Btlr	increased susceptibility to induced colitis	J:274652
Lrba^em3Btlr/Lrba^em3Btlr C57BL/6J-Lrba^em3Btlr	increased susceptibility to induced colitis	J:274652
Lrba^{Gt(OST69142)Lex}/Lrba^{Gt(OST69142)Lex} involves: 129 * 129S5/SvEvBrd	abnormal NK cell physiology	J:237187
	decreased susceptibility to graft versus host disease	J:237187
	impaired natural killer cell mediated cytotoxicity	J:237187
	increased length of allograft survival	J:237187
	increased myeloid cell number	J:237187
	increased regulatory T cell number	J:237187
Lrba^m1Btlr/Lrba^m1Btlr C57BL/6J-Lrba^m1Btlr	increased susceptibility to induced colitis	J:274652
Lrba^m2Btlr/Lrba^m2Btlr C57BL/6J-Lrba^m2Btlr	increased susceptibility to induced colitis	J:274652

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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