Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LMBRD1
  • Mouse genes Lmbrd1
  • Rat genes Lmbrd1
  • Zfish genes lmbrd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lmbrd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035612	AP-2 adaptor complex binding	Lmbrd1	IMP		Mouse	MGI:MGI:5543853|PMID:24078630
Molecular Function	GO:0032050	clathrin heavy chain binding	Lmbrd1	IDA		Mouse	MGI:MGI:5543853|PMID:24078630
Molecular Function	GO:0005158	insulin receptor binding	Lmbrd1	IDA		Mouse	PMID:24078630
Molecular Function	GO:0005515	protein binding	LMBRD1	IPI	UniProtKB:O14678	Human	PMID:25535791
Molecular Function	GO:0005515	protein binding	LMBRD1	IPI	UniProtKB:Q9Y4U1	Human	PMID:25535791
Molecular Function	GO:0005515	protein binding	LMBRD1	IPI	UniProtKB:O14678	Human	PMID:27456980
Molecular Function	GO:0005515	protein binding	LMBRD1	IPI	UniProtKB:O14678	Human	PMID:28572511
Molecular Function	GO:0005515	protein binding	LMBRD1	IPI	UniProtKB:O14678	Human	PMID:33845046
Molecular Function	GO:0005515	protein binding	Lmbrd1	IPI	UniProtKB:P15208	Mouse	MGI:MGI:5543853|PMID:24078630
Molecular Function	GO:0140318	protein transporter activity	LMBRD1	IDA		Human	PMID:27456980
Molecular Function	GO:0140318	protein transporter activity	LMBRD1	IDA		Human	PMID:33845046
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	Lmbrd1	IDA		Mouse	PMID:24078630
Cellular Component	GO:0030136	clathrin-coated vesicle	Lmbrd1	IDA		Mouse	MGI:MGI:5543853|PMID:24078630
Cellular Component	GO:0005789	endoplasmic reticulum membrane	LMBRD1	IDA		Human	PMID:27456980
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	LMBRD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	LMBRD1	IDA		Human	PMID:27456980
Cellular Component	GO:0005764	lysosome	Lmbrd1	IDA		Mouse	PMID:24078630
Cellular Component	GO:0016020	membrane	LMBRD1	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	Lmbrd1	IDA		Mouse	PMID:24078630
Biological Process	GO:0072583	clathrin-dependent endocytosis	Lmbrd1	IMP		Mouse	MGI:MGI:5543853|PMID:24078630
Biological Process	GO:0007369	gastrulation	Lmbrd1	IMP		Mouse	MGI:MGI:6508510|PMID:27061115
Biological Process	GO:0061462	protein localization to lysosome	LMBRD1	IDA		Human	PMID:27456980

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern