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Lmbrd1
Gene Detail
Symbol

Name
ID
Lmbrd1
LMBR1 domain containing 1
MGI:1915671
Synonyms
0910001K20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
10.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:24678630-24766301 bp, + strand
From VEGA annotation of GRCm38

  87672 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10156  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: LMBRD1
Gene Tree: Lmbrd1

Human
homologs
LMBRD1, LMBR1 domain containing 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 55788
neXtProt AC: NX_Q9NUN5

Human Synonyms: C6orf209, LMBD1, MAHCF, NESI

Human Chr (Location): 6q13; chr6:69675749-69797157 (-)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human LMBRD1

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice heterozygous for a targeted allele exhibit increased cardiac cell glucose uptake.
 
Interactions
Lmbrd1 interacts with 337 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(20)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase lmbrd1 ; ZFIN lmbrd1    NEW 
Molecular
reagents
All nucleic(20) cDNA(20)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000046322 (Evidence)
Ensembl Gene Model ENSMUSG00000073725 (Evidence)
Entrez Gene 68421 (Evidence)
DFCI TC1577134, TC1582662, TC1624463, TC1651075, TC1674992
DoTS DT.101161292, DT.40142222, DT.50316377, DT.94403543
Consensus CDS Project CCDS35528.1, CCDS78556.1
International Mouse Phenotyping Consortium Status Lmbrd1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046322 VEGA Gene Model | MGI Sequence Detail 87672 C57BL/6J ±  kb
transcript OTTMUST00000120742 VEGA | MGI Sequence Detail 4453 Not Applicable 
polypeptide OTTMUSP00000066757 VEGA | MGI Sequence Detail 537 Not Applicable 

For the selected sequences
All sequences(68) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(445 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006876 LMBR1-like membrane protein
Protein Ontology PR:000032677 lysosomal cobalamin transporter
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204994 Tseng LT, et al., LMBD1 protein serves as a specific adaptor for insulin receptor internalization. J Biol Chem. 2013 Nov 8;288(45):32424-32
All references(30)
Other
accession IDs
MGI:2138534

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory