MGI 5.13 - Gene Ontology Browser

Gene Ontology Browser
Term Detail

GO term:	AP-2 adaptor complex binding
Synonym:	AP-2 clathrin adaptor complex binding
GO id:	GO:0035612
Definition:	Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
Number of paths to term:	1

denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship

Gene_Ontology

molecular_function

binding

protein binding

protein complex binding

activin binding

anaphase-promoting complex binding

AP-1 adaptor complex binding

AP-2 adaptor complex binding [GO:0035612] (6 genes, 6 annotations)

AP-3 adaptor complex binding

Arp2/3 complex binding

dynein complex binding

fibrinogen binding

G-protein beta/gamma-subunit complex binding

heterotrimeric G-protein binding

immunoglobulin binding +

inhibin complex binding

insulin receptor binding

integrin binding

intermediate filament binding

mediator complex binding

mismatch repair complex binding +

proteasome binding

RNA polymerase II core binding

T cell receptor binding

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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