Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LLGL1
  • Mouse genes Llgl1
  • Rat genes Llgl1
  • Zfish genes llgl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Llgl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	Llgl1	IDA		Rat	PMID:21856246|RGD:8553614
Molecular Function	GO:0005515	protein binding	LLGL1	IPI	UniProtKB:P35580	Human	PMID:7542763
Molecular Function	GO:0019901	protein kinase binding	LLGL1	IDA		Human	PMID:7542763
Molecular Function	GO:0031267	small GTPase binding	Llgl1	IPI	UniProtKB:P35281	Rat	PMID:21856246|RGD:8553614
Cellular Component	GO:0030424	axon	Llgl1	IDA		Rat	PMID:21856246|RGD:8553614
Cellular Component	GO:0016323	basolateral plasma membrane	Llgl1	IDA		Mouse	PMID:22333836
Cellular Component	GO:0016323	basolateral plasma membrane	llgl1	IDA		Zfish	PMID:22492354
Cellular Component	GO:0030864	cortical actin cytoskeleton	LLGL1	IDA		Human	PMID:7542763
Cellular Component	GO:0005737	cytoplasm	LLGL1	IDA		Human	PMID:7542763
Cellular Component	GO:0005737	cytoplasm	Llgl1	IDA		Mouse	PMID:15037549
Cellular Component	GO:0005856	cytoskeleton	Llgl1	IDA		Mouse	MGI:MGI:3699438|PMID:7542763
Cellular Component	GO:0031901	early endosome membrane	Llgl1	IDA		Rat	PMID:21856246|RGD:8553614
Cellular Component	GO:0000137	Golgi cis cisterna	Llgl1	IDA		Rat	PMID:21856246|RGD:8553614
Cellular Component	GO:0035748	myelin sheath abaxonal region	Llgl1	IDA		Mouse	MGI:MGI:4441217|PMID:20237282
Cellular Component	GO:0032588	trans-Golgi network membrane	Llgl1	IDA		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0003171	atrioventricular valve development	llgl1	IMP	ZFIN:ZDB-GENO-210625-4	Zfish	PMID:32843528
Biological Process	GO:0003171	atrioventricular valve development	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:32843528
Biological Process	GO:0007409	axonogenesis	Llgl1	IMP		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0030031	cell projection assembly	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:27249668
Biological Process	GO:0030031	cell projection assembly	llgl1	IGI	ZFIN:ZDB-GENE-011105-1	Zfish	PMID:27249668
Biological Process	GO:0030866	cortical actin cytoskeleton organization	LLGL1	IDA		Human	PMID:7542763
Biological Process	GO:0006893	Golgi to plasma membrane transport	Llgl1	IMP		Rat	PMID:21856246|RGD:8553614
Biological Process	GO:0001947	heart looping	llgl1	IMP	ZFIN:ZDB-GENO-210625-4	Zfish	PMID:32843528
Biological Process	GO:0001947	heart looping	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:32843528
Biological Process	GO:0060887	limb epidermis development	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:32843528
Biological Process	GO:0060887	limb epidermis development	llgl1	IMP	ZFIN:ZDB-GENO-210625-4	Zfish	PMID:32843528
Biological Process	GO:0035090	maintenance of apical/basal cell polarity	Llgl1	IMP	MGI:MGI:3039269	Mouse	PMID:15037549
Biological Process	GO:0003407	neural retina development	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:22492354
Biological Process	GO:0048919	posterior lateral line neuromast development	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-11,ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:19208766
Biological Process	GO:0065003	protein-containing complex assembly	LLGL1	IDA		Human	PMID:7542763
Biological Process	GO:0008593	regulation of Notch signaling pathway	llgl1	IMP	ZFIN:ZDB-MRPHLNO-100419-12	Zfish	PMID:22492354

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern