Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KMT2C
  • Mouse genes Kmt2c
  • Rat genes Kmt2c
  • Zfish genes kmt2ca,kmt2cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kmt2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	KMT2C	IDA		Human	PMID:17500065
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	Kmt2c	IDA		Mouse	MGI:MGI:3846030|PMID:18172164
Molecular Function	GO:0042054	histone methyltransferase activity	KMT2C	IDA		Human	PMID:22266653
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:Q14686	Human	PMID:12482968
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:Q14686	Human	PMID:17021013
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:P61964	Human	PMID:17500065
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:Q14686	Human	PMID:19047629
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:Q14686	Human	PMID:19433796
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:P61964	Human	PMID:22266653
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:P61964	Human	PMID:22665483
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:Q14686	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:P61964	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:Q9UBL3-3	Human	PMID:26886794
Molecular Function	GO:0005515	protein binding	KMT2C	IPI	UniProtKB:P61964	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	Kmt2c	IPI	PR:Q9JL19	Mouse	PMID:17021013
Molecular Function	GO:0003723	RNA binding	KMT2C	HDA		Human	PMID:22658674
Cellular Component	GO:0035097	histone methyltransferase complex	KMT2C	IDA		Human	PMID:17500065
Cellular Component	GO:0044666	MLL3/4 complex	KMT2C	IPI		Human	PMID:23508102
Cellular Component	GO:0044666	MLL3/4 complex	KMT2C	IDA		Human	PMID:17500065
Cellular Component	GO:0005634	nucleus	KMT2C	IDA		Human	PMID:17500065
Biological Process	GO:0061029	eyelid development in camera-type eye	Kmt2c	IMP	MGI:MGI:3693319	Mouse	PMID:17021013
Biological Process	GO:0035264	multicellular organism growth	Kmt2c	IMP	MGI:MGI:3693319	Mouse	PMID:17021013
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Kmt2c	IMP	MGI:MGI:3693319	Mouse	PMID:17021013
Biological Process	GO:0010468	regulation of gene expression	Kmt2c	IMP		Mouse	PMID:17021013
Biological Process	GO:0051602	response to electrical stimulus	Kmt2c	IEP		Rat	PMID:27207907|RGD:151356765
Biological Process	GO:0007338	single fertilization	Kmt2c	IMP	MGI:MGI:3693319	Mouse	PMID:17021013

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern