Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kif5b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KIF5B
- Mouse genes Kif5b
- Rat genes Kif5b
- Zfish genes kif5ba,kif5bb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	KIF5B	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	KIF5B	IPI	UniProtKB:P33176	Human	PMID:17013387
Molecular Function	GO:0042802	identical protein binding	KIF5B	IPI	UniProtKB:P33176	Human	PMID:18004302
Molecular Function	GO:0008432	JUN kinase binding	Kif5b	IPI	RGD:621506	Rat	PMID:18932217\|RGD:9587790
Molecular Function	GO:0008017	microtubule binding	KIF5B	IDA		Human	PMID:28426968
Molecular Function	GO:0008017	microtubule binding	Kif5b	IDA		Rat	PMID:14985359\|RGD:8553555
Molecular Function	GO:0099609	microtubule lateral binding	Kif5b	IMP		Rat	PMID:15147841\|RGD:12793044
Molecular Function	GO:0003777	microtubule motor activity	KIF5B	IDA		Human	PMID:28426968
Molecular Function	GO:0003777	microtubule motor activity	Kif5b	IDA		Rat	PMID:14985359\|RGD:8553555
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q8CII8	Human	PMID:19164528
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q9BQS8	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P68619	Human	PMID:21915095
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q9BQS8	Human	PMID:25855459
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P15146	Human	PMID:28426968
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P31323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P52954	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P62487	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q01850	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q96BR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KIF5B	IPI	UniProtKB:Q96CN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:O88485	Mouse	MGI:MGI:6093100\|PMID:17548833
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:O88447	Mouse	MGI:MGI:1266918\|PMID:9624122
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:Q3TXX3	Mouse	MGI:MGI:5795817\|PMID:21976701
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:O35685\|UniProtKB:O88485	Mouse	MGI:MGI:4430931\|PMID:20019668
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:O88448	Mouse	MGI:MGI:1266918\|PMID:9624122
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:Q8R1Z4	Mouse	MGI:MGI:5298338\|PMID:19886865
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	PR:P28738	Mouse	PMID:10964943
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	PR:Q9QWT9	Mouse	PMID:17360972
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:Q63100	Rat	PMID:14985359\|RGD:8553555
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:P37840	Rat	PMID:16176937\|RGD:8554467
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	RGD:2950	Rat	PMID:17241275\|RGD:11059543
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:P09456	Rat	PMID:17610895\|RGD:126781731
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	RGD:619708	Rat	PMID:17669366\|RGD:2316312
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	RGD:621227	Rat	PMID:18932217\|RGD:9587790
Molecular Function	GO:0005515	protein binding	Kif5b	IPI	UniProtKB:Q9UPV9	Rat	PMID:24995978\|RGD:9590184
Molecular Function	GO:0005515	protein binding	kif5ba	IPI	UniProtKB:D3KVM1	Zfish	PMID:20150281
Molecular Function	GO:0044877	protein-containing complex binding	Kif5b	IDA		Mouse	PMID:29276473
Cellular Component	GO:0044295	axonal growth cone	Kif5b	IDA		Rat	PMID:23487040\|RGD:11059540
Cellular Component	GO:0034451	centriolar satellite	KIF5B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035253	ciliary rootlet	Kif5b	IDA		Mouse	PMID:16018997
Cellular Component	GO:0005737	cytoplasm	Kif5b	IDA		Mouse	PMID:16018997
Cellular Component	GO:0005737	cytoplasm	Kif5b	IDA		Rat	PMID:25462067\|RGD:11059539
Cellular Component	GO:0005829	cytosol	KIF5B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030139	endocytic vesicle	Kif5b	IDA		Mouse	PMID:17360972
Cellular Component	GO:0016020	membrane	KIF5B	HDA		Human	PMID:19946888
Cellular Component	GO:0043227	membrane-bounded organelle	Kif5b	IDA		Mouse	PMID:12805290
Cellular Component	GO:0015630	microtubule cytoskeleton	Kif5b	IDA		Rat	PMID:15147841\|RGD:12793044
Cellular Component	GO:0005739	mitochondrion	Kif5b	IDA		Mouse	PMID:34048705
Cellular Component	GO:0043005	neuron projection	Kif5b	IDA		Mouse	PMID:16301330
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Kif5b	IDA		Rat	PMID:14985359\|RGD:8553555
Cellular Component	GO:0045335	phagocytic vesicle	Kif5b	IDA		Mouse	PMID:19144319
Cellular Component	GO:0031982	vesicle	KIF5B	IDA		Human	PMID:20682791
Biological Process	GO:0099641	anterograde axonal protein transport	Kif5b	IMP		Rat	PMID:23576431\|RGD:13673742
Biological Process	GO:0060349	bone morphogenesis	kif5ba	IGI	ZFIN:ZDB-GENE-070629-4	Zfish	PMID:28715414
Biological Process	GO:0060349	bone morphogenesis	kif5bb	IGI	ZFIN:ZDB-GENE-070629-2	Zfish	PMID:28715414
Biological Process	GO:0007420	brain development	Kif5b	IEP		Rat	PMID:9349526\|RGD:12792964
Biological Process	GO:0051216	cartilage development	kif5ba	IGI	ZFIN:ZDB-GENE-070629-4	Zfish	PMID:28715414
Biological Process	GO:0051216	cartilage development	kif5bb	IGI	ZFIN:ZDB-GENE-070629-2	Zfish	PMID:28715414
Biological Process	GO:0071346	cellular response to type II interferon	Kif5b	IDA		Mouse	PMID:19144319
Biological Process	GO:0051642	centrosome localization	KIF5B	IMP		Human	PMID:20386726
Biological Process	GO:0007028	cytoplasm organization	Kif5b	IMP	MGI:MGI:2159694	Mouse	PMID:9657148
Biological Process	GO:0007281	germ cell development	kif5ba	IMP	ZFIN:ZDB-GENO-160122-21	Zfish	PMID:26253407
Biological Process	GO:0021766	hippocampus development	Kif5b	IEP		Rat	PMID:9349526\|RGD:12792964
Biological Process	GO:0032418	lysosome localization	KIF5B	IMP		Human	PMID:22172677
Biological Process	GO:0047497	mitochondrion transport along microtubule	Kif5b	IMP		Mouse	PMID:34048705
Biological Process	GO:0160040	mitocytosis	Kif5b	IMP		Mouse	PMID:34048705
Biological Process	GO:0042267	natural killer cell mediated cytotoxicity	KIF5B	IMP		Human	PMID:24088571
Biological Process	GO:0072383	plus-end-directed vesicle transport along microtubule	Kif5b	IMP		Mouse	PMID:17360972
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Kif5b	IMP		Rat	PMID:25462067\|RGD:11059539
Biological Process	GO:0090316	positive regulation of intracellular protein transport	Kif5b	IMP		Rat	PMID:17241275\|RGD:11059543
Biological Process	GO:0043268	positive regulation of potassium ion transport	KIF5B	IDA		Human	PMID:19675065
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	KIF5B	IDA		Human	PMID:19675065
Biological Process	GO:0032230	positive regulation of synaptic transmission, GABAergic	Kif5b	IDA		Mouse	MGI:MGI:5582163\|PMID:20152113
Biological Process	GO:0031340	positive regulation of vesicle fusion	Kif5b	IMP		Rat	PMID:24203699\|RGD:11059541
Biological Process	GO:1905152	positive regulation of voltage-gated sodium channel activity	Kif5b	IMP		Rat	PMID:24198377\|RGD:11073607
Biological Process	GO:0042391	regulation of membrane potential	KIF5B	IDA		Human	PMID:19675065
Biological Process	GO:1990049	retrograde neuronal dense core vesicle transport	Kif5b	IGI	UniProtKB:Q6QLM7	Rat	PMID:28426968\|RGD:13514087
Biological Process	GO:0007519	skeletal muscle tissue development	kif5ba	IGI	ZFIN:ZDB-GENE-070629-4	Zfish	PMID:28715414
Biological Process	GO:0007519	skeletal muscle tissue development	kif5bb	IGI	ZFIN:ZDB-GENE-070629-2	Zfish	PMID:28715414
Biological Process	GO:0035617	stress granule disassembly	Kif5b	IMP		Mouse	MGI:MGI:4397616\|PMID:19825938
Biological Process	GO:0047496	vesicle transport along microtubule	KIF5B	IDA		Human	PMID:28426968
Biological Process	GO:0047496	vesicle transport along microtubule	Kif5b	IGI	MGI:MGI:109596	Mouse	PMID:17360972
Biological Process	GO:0047496	vesicle transport along microtubule	Kif5b	IDA		Rat	PMID:14985359\|RGD:8553555

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.