Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KDM4D
  • Mouse genes Kdm4d
  • Rat genes Kdm4d
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kdm4d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	Kdm4d	IDA		Mouse	PMID:6953429
Molecular Function	GO:0003684	damaged DNA binding	Kdm4d	IDA		Mouse	PMID:24550317
Molecular Function	GO:0032452	histone demethylase activity	Kdm4d	IDA		Mouse	PMID:19144645
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM4D	IDA		Human	PMID:25124442
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm4d	IMP	MGI:MGI:5051955	Mouse	PMID:21293030
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm4d	IDA		Mouse	PMID:16738407
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm4d	IMP		Mouse	PMID:24550317
Molecular Function	GO:0140684	histone H3K9me2/H3K9me3 demethylase activity	KDM4D	IDA		Human	PMID:21914792
Molecular Function	GO:0005515	protein binding	KDM4D	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Cellular Component	GO:0072562	blood microparticle	KDM4D	HDA		Human	PMID:22516433
Cellular Component	GO:0005634	nucleus	Kdm4d	IDA		Mouse	PMID:24550317
Cellular Component	GO:0005721	pericentric heterochromatin	Kdm4d	IDA		Mouse	PMID:16738407
Cellular Component	GO:0035861	site of double-strand break	KDM4D	IDA		Human	PMID:24550317
Cellular Component	GO:0035861	site of double-strand break	Kdm4d	IDA		Mouse	PMID:24550317
Biological Process	GO:0071479	cellular response to ionizing radiation	KDM4D	IMP		Human	PMID:24550317
Biological Process	GO:0006974	DNA damage response	Kdm4d	IDA		Mouse	PMID:24550317
Biological Process	GO:0000724	double-strand break repair via homologous recombination	KDM4D	IMP		Human	PMID:24550317
Biological Process	GO:0016570	histone modification	Kdm4d	IDA		Mouse	MGI:MGI:3845989|PMID:19144645
Biological Process	GO:0035563	positive regulation of chromatin binding	KDM4D	IMP		Human	PMID:24550317
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	KDM4D	IMP		Human	PMID:24550317
Biological Process	GO:0001932	regulation of protein phosphorylation	KDM4D	IMP		Human	PMID:24550317

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern