Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnj10

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNJ10
- Mouse genes Kcnj10
- Rat genes Kcnj10
- Zfish genes kcnj10a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnj10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Kcnj10	IPI	RGD:61822	Rat	PMID:16206160\|RGD:2326044
Molecular Function	GO:0005242	inward rectifier potassium channel activity	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:20074622
Molecular Function	GO:0005242	inward rectifier potassium channel activity	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:19515915
Molecular Function	GO:0005242	inward rectifier potassium channel activity	kcnj10a	IDA		Zfish	PMID:23471908
Molecular Function	GO:0005267	potassium channel activity	Kcnj10	IDA		Mouse	PMID:9647694
Molecular Function	GO:0005515	protein binding	KCNJ10	IPI	UniProtKB:Q15049	Human	PMID:17628813
Molecular Function	GO:0005515	protein binding	KCNJ10	IPI	UniProtKB:Q15049	Human	PMID:19931615
Molecular Function	GO:0005515	protein binding	KCNJ10	IPI	UniProtKB:A0A8I3NPD4	Human	PMID:24561201
Molecular Function	GO:0005515	protein binding	KCNJ10	IPI	UniProtKB:Q8IUQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	PR:Q99L88	Mouse	PMID:15310750
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	PR:Q61234	Mouse	PMID:15310750
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	PR:Q61235	Mouse	PMID:15310750
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	PR:Q63ZW7	Mouse	PMID:9647694
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	RGD:61824	Rat	PMID:10856114\|RGD:2326048
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	RGD:1307068	Rat	PMID:15024025\|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	RGD:2507	Rat	PMID:15024025\|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	RGD:1318392	Rat	PMID:19931615\|RGD:2326037
Molecular Function	GO:0005515	protein binding	Kcnj10	IPI	UniProtKB:Q15049	Rat	PMID:19931615\|RGD:2326037
Molecular Function	GO:0005102	signaling receptor binding	Kcnj10	IPI	RGD:2277	Rat	PMID:21084311\|RGD:7206833
Cellular Component	GO:0016324	apical plasma membrane	Kcnj10	IDA		Rat	PMID:18395087\|RGD:2317968
Cellular Component	GO:0097449	astrocyte projection	Kcnj10	IDA		Mouse	MGI:MGI:5629870\|PMID:25716834
Cellular Component	GO:0097449	astrocyte projection	Kcnj10	IDA		Rat	PMID:20833221\|RGD:8662899
Cellular Component	GO:0016323	basolateral plasma membrane	Kcnj10	IDA		Mouse	PMID:20651251
Cellular Component	GO:0016323	basolateral plasma membrane	Kcnj10	IDA		Rat	PMID:18303016\|RGD:2326040
Cellular Component	GO:0044297	cell body	Kcnj10	IDA		Mouse	MGI:MGI:5629870\|PMID:25716834
Cellular Component	GO:0097546	ciliary base	Kcnj10	IDA		Mouse	PMID:26546361
Cellular Component	GO:0005902	microvillus	Kcnj10	IDA		Rat	PMID:20466875\|RGD:2326033
Cellular Component	GO:0005886	plasma membrane	Kcnj10	IDA		Mouse	PMID:15310750
Biological Process	GO:0007628	adult walking behavior	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0007628	adult walking behavior	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:10908613
Biological Process	GO:0035865	cellular response to potassium ion	Kcnj10	IMP	MGI:MGI:3761690	Mouse	PMID:31736353
Biological Process	GO:0022010	central nervous system myelination	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0051649	establishment of localization in cell	Kcnj10	IMP		Mouse	PMID:17869537
Biological Process	GO:0051649	establishment of localization in cell	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:10908613
Biological Process	GO:0051649	establishment of localization in cell	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:19515915
Biological Process	GO:0051649	establishment of localization in cell	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:20074622
Biological Process	GO:0051935	glutamate reuptake	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0006954	inflammatory response	Kcnj10	IEP		Rat	PMID:15748953\|RGD:2326045
Biological Process	GO:0001822	kidney development	kcnj10a	IMP	ZFIN:ZDB-MRPHLNO-130726-1	Zfish	PMID:23471908
Biological Process	GO:0051938	L-glutamate import	Kcnj10	IMP		Rat	PMID:17091490\|RGD:2326042
Biological Process	GO:0008345	larval locomotory behavior	kcnj10a	IMP	ZFIN:ZDB-MRPHLNO-130726-2	Zfish	PMID:27677466
Biological Process	GO:0040011	locomotion	kcnj10a	IMP	ZFIN:ZDB-MRPHLNO-130726-1	Zfish	PMID:24244558
Biological Process	GO:0040011	locomotion	kcnj10a	IMP	ZFIN:ZDB-MRPHLNO-130726-2	Zfish	PMID:24244558
Biological Process	GO:0007626	locomotory behavior	kcnj10a	IMP	ZFIN:ZDB-MRPHLNO-130726-1	Zfish	PMID:23471908
Biological Process	GO:0060081	membrane hyperpolarization	Kcnj10	IMP		Rat	PMID:17091490\|RGD:2326042
Biological Process	GO:1905515	non-motile cilium assembly	Kcnj10	IMP		Mouse	PMID:26546361
Biological Process	GO:0014003	oligodendrocyte development	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0021554	optic nerve development	Kcnj10	IEP		Rat	PMID:15198689\|RGD:2326047
Biological Process	GO:0055075	potassium ion homeostasis	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0055075	potassium ion homeostasis	Kcnj10	IMP		Mouse	PMID:16306174
Biological Process	GO:1990573	potassium ion import across plasma membrane	Kcnj10	IMP		Rat	PMID:17091490\|RGD:2326042
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:20074622
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:10908613
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnj10	IMP		Mouse	PMID:17869537
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:19515915
Biological Process	GO:0006813	potassium ion transport	Kcnj10	IDA		Mouse	PMID:9647694
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0042391	regulation of membrane potential	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:19515915
Biological Process	GO:0042391	regulation of membrane potential	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:20074622
Biological Process	GO:0060075	regulation of resting membrane potential	Kcnj10	IMP	MGI:MGI:3655847,MGI:MGI:3761690	Mouse	PMID:17942730
Biological Process	GO:0060075	regulation of resting membrane potential	Kcnj10	IMP		Mouse	PMID:16306174
Biological Process	GO:0060075	regulation of resting membrane potential	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:10908613
Biological Process	GO:0051930	regulation of sensory perception of pain	Kcnj10	IMP		Rat	PMID:18417695\|RGD:2326039
Biological Process	GO:0009637	response to blue light	Kcnj10	IEP		Rat	PMID:18450590\|RGD:2326038
Biological Process	GO:0051384	response to glucocorticoid	Kcnj10	IEP		Rat	PMID:20466875\|RGD:2326033
Biological Process	GO:0051385	response to mineralocorticoid	Kcnj10	IEP		Rat	PMID:20466875\|RGD:2326033
Biological Process	GO:0036268	swimming	kcnj10a	IMP	ZFIN:ZDB-MRPHLNO-130726-1	Zfish	PMID:23471908
Biological Process	GO:0007601	visual perception	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:15359216
Biological Process	GO:0007601	visual perception	Kcnj10	IMP	MGI:MGI:2182467	Mouse	PMID:10908613

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.