Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNAB2
  • Mouse genes Kcnab2
  • Rat genes Kcnab2
  • Zfish genes kcnab2a,kcnab2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnab2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004033	aldo-keto reductase (NADP) activity	Kcnab2	IDA		Rat	PMID:18672894|RGD:10047329
Molecular Function	GO:0015459	potassium channel regulator activity	KCNAB2	IDA		Human	PMID:7649300
Molecular Function	GO:0015459	potassium channel regulator activity	Kcnab2	IDA		Rat	PMID:9763623|RGD:10047178
Molecular Function	GO:0005515	protein binding	KCNAB2	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNAB2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Kcnab2	IPI	UniProtKB:Q9CPW0	Mouse	PMID:25707359
Molecular Function	GO:0005515	protein binding	Kcnab2	IPI	PR:P63143	Mouse	PMID:15662035
Molecular Function	GO:0005515	protein binding	Kcnab2	IPI	RGD:1307076	Rat	PMID:10624965|RGD:8554062
Molecular Function	GO:0005515	protein binding	Kcnab2	IPI	RGD:69287	Rat	PMID:12431995|RGD:634214
Molecular Function	GO:0044877	protein-containing complex binding	Kcnab2	IPI	RGD:3399|RGD:69287	Rat	PMID:10477520|RGD:1642693
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnab2	IPI	RGD:2950	Rat	PMID:8756417|RGD:9743934
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnab2	IPI	RGD:61827	Rat	PMID:8756417|RGD:9743934
Cellular Component	GO:0030424	axon	Kcnab2	IDA		Mouse	PMID:24211303
Cellular Component	GO:0030424	axon	Kcnab2	IDA		Rat	PMID:21357749|RGD:10047144
Cellular Component	GO:0043194	axon initial segment	Kcnab2	IDA		Mouse	PMID:18509034
Cellular Component	GO:0043679	axon terminus	Kcnab2	IDA		Mouse	MGI:MGI:2178002|PMID:11825900
Cellular Component	GO:0005829	cytosol	Kcnab2	IDA		Rat	PMID:21357749|RGD:10047144
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	Kcnab2	IDA		Rat	PMID:23318870|RGD:10047174
Cellular Component	GO:0098978	glutamatergic synapse	Kcnab2	IDA		Rat	PMID:24211303|RGD:155230810
Cellular Component	GO:0098978	glutamatergic synapse	Kcnab2	IMP		Rat	PMID:24211303|RGD:155230810
Cellular Component	GO:0044224	juxtaparanode region of axon	KCNAB2	IDA		Human	PMID:11086297
Cellular Component	GO:0044224	juxtaparanode region of axon	Kcnab2	IDA		Mouse	MGI:MGI:2675531|PMID:12963709
Cellular Component	GO:0044224	juxtaparanode region of axon	Kcnab2	IDA		Mouse	MGI:MGI:2178002|PMID:11825900
Cellular Component	GO:0044224	juxtaparanode region of axon	Kcnab2	IDA		Rat	PMID:9334400|RGD:10047182
Cellular Component	GO:0016020	membrane	KCNAB2	IDA		Human	PMID:11086297
Cellular Component	GO:0005874	microtubule	Kcnab2	IDA		Rat	PMID:21357749|RGD:10047144
Cellular Component	GO:0043005	neuron projection	Kcnab2	IDA		Rat	PMID:23318870|RGD:10047174
Cellular Component	GO:1990031	pinceau fiber	Kcnab2	IDA		Rat	PMID:9334400|RGD:10047182
Cellular Component	GO:0014069	postsynaptic density	Kcnab2	IDA		Mouse	PMID:24211303
Cellular Component	GO:0098839	postsynaptic density membrane	Kcnab2	IDA		Rat	PMID:24211303|RGD:155230810
Cellular Component	GO:0098839	postsynaptic density membrane	Kcnab2	IMP		Rat	PMID:24211303|RGD:155230810
Cellular Component	GO:0034705	potassium channel complex	Kcnab2	IDA		Rat	PMID:23318870|RGD:10047174
Cellular Component	GO:0034705	potassium channel complex	Kcnab2	IDA		Rat	PMID:9334400|RGD:10047182
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNAB2	IDA		Human	PMID:11086297
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Kcnab2	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0045445	myoblast differentiation	Kcnab2	IEP		Rat	PMID:12652645|RGD:9743957
Biological Process	GO:0070995	NADPH oxidation	Kcnab2	IDA		Rat	PMID:18672894|RGD:10047329
Biological Process	GO:0050905	neuromuscular process	Kcnab2	IMP		Mouse	MGI:MGI:2178002|PMID:11825900
Biological Process	GO:0098900	regulation of action potential	kcnab2b	IMP	ZFIN:ZDB-MRPHLNO-140516-1	Zfish	PMID:24335214
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	KCNAB2	IDA		Human	PMID:7649300
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	Kcnab2	IDA		Rat	PMID:9763623|RGD:10047178
Biological Process	GO:2000008	regulation of protein localization to cell surface	Kcnab2	IMP		Rat	PMID:21357749|RGD:10047144
Biological Process	GO:0051969	regulation of transmission of nerve impulse	kcnab2b	IMP	ZFIN:ZDB-MRPHLNO-140516-1	Zfish	PMID:24335214

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern