Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INHBA
  • Mouse genes Inhba
  • Rat genes Inhba
  • Zfish genes inhbaa,inhbab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inhba

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	INHBA	IDA		Human	PMID:9884026
Molecular Function	GO:0042802	identical protein binding	INHBA	IPI	UniProtKB:P08476	Human	PMID:2575216
Molecular Function	GO:0017046	peptide hormone binding	INHBA	IPI	UniProtKB:P19883	Human	PMID:16198295
Molecular Function	GO:0005515	protein binding	INHBA	IPI	UniProtKB:O95633	Human	PMID:12697670
Molecular Function	GO:0005515	protein binding	INHBA	IPI	UniProtKB:P21674	Human	PMID:16482217
Molecular Function	GO:0005515	protein binding	INHBA	IPI	UniProtKB:P05111	Human	PMID:2575216
Molecular Function	GO:0005515	protein binding	INHBA	IPI	UniProtKB:P09529	Human	PMID:2575216
Molecular Function	GO:0005515	protein binding	INHBA	IPI	UniProtKB:P27037	Human	PMID:9032295
Molecular Function	GO:0044877	protein-containing complex binding	Inhba	IDA		Rat	PMID:8994390|RGD:2290410
Molecular Function	GO:0005102	signaling receptor binding	Inhba	IPI	PR:P37172	Mouse	PMID:1646080
Molecular Function	GO:0005102	signaling receptor binding	Inhba	IPI	PR:Q61271	Mouse	PMID:1646080
Molecular Function	GO:0005102	signaling receptor binding	Inhba	IPI	PR:P37172	Mouse	PMID:7577669
Molecular Function	GO:0005102	signaling receptor binding	Inhba	IPI	PR:Q61271	Mouse	PMID:7577669
Molecular Function	GO:0070699	type II activin receptor binding	INHBA	IPI	UniProtKB:P27038	Human	PMID:7890768
Molecular Function	GO:0070699	type II activin receptor binding	INHBA	IPI	UniProtKB:P36896	Human	PMID:7890768
Cellular Component	GO:0043509	activin A complex	INHBA	IDA		Human	PMID:7890768
Cellular Component	GO:0005576	extracellular region	INHBA	IDA		Human	PMID:12213882
Cellular Component	GO:0005615	extracellular space	Inhba	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Inhba	IDA		Rat	PMID:17636211|RGD:9743910
Cellular Component	GO:0043512	inhibin A complex	INHBA	IDA		Human	PMID:7890768
Cellular Component	GO:0043512	inhibin A complex	Inhba	IDA		Rat	PMID:8994390|RGD:2290410
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Inhba	IDA		Mouse	PMID:8133077
Biological Process	GO:0032924	activin receptor signaling pathway	INHBA	IDA		Human	PMID:9884026
Biological Process	GO:0060936	cardiac fibroblast cell development	Inhba	IDA		Rat	PMID:27477354|RGD:151665478
Biological Process	GO:0110021	cardiac muscle myoblast proliferation	inhbaa	IMP	ZFIN:ZDB-GENO-181112-4	Zfish	PMID:29196619
Biological Process	GO:0110021	cardiac muscle myoblast proliferation	inhbaa	IMP	ZFIN:ZDB-GENO-181121-5	Zfish	PMID:29196619
Biological Process	GO:1904385	cellular response to angiotensin	Inhba	IEP		Rat	PMID:27477354|RGD:151665478
Biological Process	GO:0071397	cellular response to cholesterol	Inhba	IDA		Rat	PMID:19464342|RGD:8554083
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Inhba	IDA		Rat	PMID:19464342|RGD:8554083
Biological Process	GO:0035987	endodermal cell differentiation	INHBA	IDA		Human	PMID:21828274
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	INHBA	IDA		Human	PMID:9884026
Biological Process	GO:0061029	eyelid development in camera-type eye	Inhba	IGI	UniProtKB:Q04999	Mouse	MGI:MGI:2682175|PMID:14551263
Biological Process	GO:0031101	fin regeneration	inhbaa	IMP	ZFIN:ZDB-GENO-071129-4	Zfish	PMID:17683938
Biological Process	GO:0031101	fin regeneration	inhbaa	IMP	ZFIN:ZDB-MRPHLNO-071129-2	Zfish	PMID:17683938
Biological Process	GO:0097154	GABAergic neuron differentiation	INHBA	IDA		Human	PMID:25804741
Biological Process	GO:0001942	hair follicle development	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	INHBA	IDA		Human	PMID:15451575
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Inhba	IDA		Mouse	PMID:7799920
Biological Process	GO:0042541	hemoglobin biosynthetic process	INHBA	IDA		Human	PMID:1310063
Biological Process	GO:0008584	male gonad development	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0001707	mesoderm formation	Inhba	IDA		Mouse	PMID:7799920
Biological Process	GO:0048333	mesodermal cell differentiation	Inhba	IDA		Mouse	PMID:7799920
Biological Process	GO:0010259	multicellular organism aging	Inhba	IEP		Rat	PMID:17636211|RGD:9743910
Biological Process	GO:0030308	negative regulation of cell growth	INHBA	IDA		Human	PMID:20573232
Biological Process	GO:0030308	negative regulation of cell growth	INHBA	IDA		Human	PMID:9884026
Biological Process	GO:0008285	negative regulation of cell population proliferation	INHBA	IDA		Human	PMID:11948405
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	INHBA	IDA		Human	PMID:9884026
Biological Process	GO:0042476	odontogenesis	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0001541	ovarian follicle development	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	Inhba	IDA		Rat	PMID:27477354|RGD:151665478
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	INHBA	IDA		Human	PMID:21281489
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Inhba	IGI	UniProtKB:Q04999	Mouse	MGI:MGI:2682175|PMID:14551263
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Inhba	IDA		Rat	PMID:27477354|RGD:151665478
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	INHBA	IDA		Human	PMID:9032295
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	INHBA	IDA		Human	PMID:8267637
Biological Process	GO:0010628	positive regulation of gene expression	INHBA	IDA		Human	PMID:23812417
Biological Process	GO:0060279	positive regulation of ovulation	Inhba	IMP		Mouse	MGI:MGI:3758367|PMID:17609433
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	INHBA	IDA		Human	PMID:19736306
Biological Process	GO:0051247	positive regulation of protein metabolic process	INHBA	IDA		Human	PMID:21828274
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Inhba	IDA		Rat	PMID:23567549|RGD:151893499
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	INHBA	IDA		Human	PMID:12702211
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	INHBA	IDA		Human	PMID:21281489
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Inhba	IDA		Mouse	PMID:10391928
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Inhba	IDA		Rat	PMID:23567549|RGD:151893499
Biological Process	GO:0045945	positive regulation of transcription by RNA polymerase III	Inhba	IEP		Rat	PMID:23567549|RGD:151893499
Biological Process	GO:0042701	progesterone secretion	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0046880	regulation of follicle-stimulating hormone secretion	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	INHBA	IDA		Human	PMID:11948405
Biological Process	GO:0009410	response to xenobiotic stimulus	INHBA	IDA		Human	PMID:20573232
Biological Process	GO:0060021	roof of mouth development	INHBA	IGI	UniProtKB:Q04999	Human	PMID:10932194
Biological Process	GO:0021773	striatal medium spiny neuron differentiation	INHBA	IDA		Human	PMID:25804741
Biological Process	GO:0006366	transcription by RNA polymerase II	Inhba	IDA		Mouse	PMID:10391928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern