Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IL1RL1
  • Mouse genes Il1rl1
  • Rat genes Il1rl1
  • Zfish genes il1rl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Il1rl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002113	interleukin-33 binding	Il1rl1	IPI	UniProtKB:Q8BVZ5	Mouse	MGI:MGI:6141045|PMID:29045903
Molecular Function	GO:0005515	protein binding	IL1RL1	IPI	UniProtKB:O95760	Human	PMID:16286016
Molecular Function	GO:0005515	protein binding	IL1RL1	IPI	UniProtKB:Q9BXN2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IL1RL1	IPI	UniProtKB:Q13445	Human	PMID:8621446
Molecular Function	GO:0005515	protein binding	Il1rl1	IPI	UniProtKB:Q61730	Mouse	MGI:MGI:4353496|PMID:17675517
Molecular Function	GO:0005515	protein binding	Il1rl1	IPI	UniProtKB:Q61730	Mouse	MGI:MGI:3764000|PMID:18003919
Molecular Function	GO:0005515	protein binding	Il1rl1	IPI	UniProtKB:Q6PCT2	Mouse	MGI:MGI:5437589|PMID:22660580
Cellular Component	GO:0009986	cell surface	Il1rl1	IDA		Rat	PMID:8131748|RGD:69859
Cellular Component	GO:0005829	cytosol	IL1RL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009897	external side of plasma membrane	Il1rl1	IDA		Mouse	PMID:19666510
Cellular Component	GO:0009897	external side of plasma membrane	Il1rl1	IDA		Mouse	PMID:12714518
Cellular Component	GO:0009897	external side of plasma membrane	Il1rl1	IDA		Rat	PMID:8131748|RGD:69859
Cellular Component	GO:0005615	extracellular space	Il1rl1	IDA		Rat	PMID:20014349|RGD:2316352
Cellular Component	GO:0005925	focal adhesion	IL1RL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	IL1RL1	IDA		Human	GO_REF:0000052
Biological Process	GO:0071260	cellular response to mechanical stimulus	Il1rl1	IEP		Rat	PMID:17492053|RGD:40813740
Biological Process	GO:1901653	cellular response to peptide	Il1rl1	IEP		Rat	PMID:18406357|RGD:2316543
Biological Process	GO:0006954	inflammatory response	Il1rl1	IMP		Mouse	MGI:MGI:6856556|PMID:34644537
Biological Process	GO:0030225	macrophage differentiation	Il1rl1	IMP		Mouse	MGI:MGI:6856556|PMID:34644537
Biological Process	GO:0008285	negative regulation of cell population proliferation	Il1rl1	IDA		Rat	PMID:20014349|RGD:2316352
Biological Process	GO:0002826	negative regulation of T-helper 1 type immune response	Il1rl1	IGI	UniProtKB:P08226	Mouse	MGI:MGI:3775141|PMID:18268038
Biological Process	GO:0032689	negative regulation of type II interferon production	Il1rl1	IGI	UniProtKB:P08226	Mouse	MGI:MGI:3775141|PMID:18268038
Biological Process	GO:0032722	positive regulation of chemokine production	Il1rl1	IMP		Mouse	MGI:MGI:4430159|PMID:19841166
Biological Process	GO:0050729	positive regulation of inflammatory response	Il1rl1	IMP		Mouse	MGI:MGI:4430159|PMID:19841166
Biological Process	GO:0032754	positive regulation of interleukin-5 production	Il1rl1	IGI	UniProtKB:P08226	Mouse	MGI:MGI:3775141|PMID:18268038
Biological Process	GO:0043032	positive regulation of macrophage activation	Il1rl1	IMP		Mouse	MGI:MGI:4430159|PMID:19841166
Biological Process	GO:0031667	response to nutrient levels	Il1rl1	IEP		Rat	PMID:24265755|RGD:40818078

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern