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Il1rl1
Gene Detail
Symbol

Name
ID
Il1rl1
interleukin 1 receptor-like 1
MGI:98427
STS
Synonyms
DER4, Fit-1, Ly84, St2, ST2, ST2L, St2-rs1, T1, T1 gene, T1/ST2
Feature Type
protein coding gene
Genetic Map
Chromosome 1
19.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:40429570-40465415 bp, + strand
From VEGA annotation of GRCm38

  35846 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2862  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: interleukin-1 receptor type I
Gene Tree: Il1rl1

Human
homologs
Human Homolog IL1RL1, interleukin 1 receptor-like 1
NCBI Gene ID 9173
neXtProt AC  NX_Q01638
Human Synonyms  DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1
Human Chr (Location)  2q12; chr2:102311502-102352332 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display an abnormal Th2 type inflammatory response.
 
Interactions
Il1rl1 interacts with 305 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (83)    Tissues (31)    Images (23)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 23
RNase protection 60
cDNA source data(52)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(55) Genomic(3) cDNA(52)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000037806 (Evidence)
Ensembl Gene ModelENSMUSG00000026069 (Evidence)
Entrez Gene17082 (Evidence)
UniGene289824
DFCITC1601736, TC1579281
DoTSDT.55100927, DT.101723639, DT.101365331
NIA Mouse Gene IndexU042155
Consensus CDS ProjectCCDS35548.1, CCDS56626.1
International Mouse Knockout Project StatusIl1rl1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037806 VEGA Gene Model | MGI Sequence Detail 35846 C57BL/6J ±  kb
transcript OTTMUST00000097562 VEGA | MGI Sequence Detail 5302 Not Applicable 
polypeptide OTTMUSP00000054731 VEGA | MGI Sequence Detail 567 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(12) UniProt(7)
Polymorphisms
RFLP(1) : SNPs within 2kb(349 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR015621 Interleukin-1 receptor family
InterPro IPR004074 Interleukin-1 receptor, type I/II
InterPro IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Protein Ontology PR:000008994 interleukin-1 receptor-like 1
References
(Earliest) J:9936 Klemenz R, et al., Serum- and oncoprotein-mediated induction of a gene with sequence similarity to the gene encoding carcinoembryonic antigen. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5708-12
(Latest) J:213357 Llop-Guevara A, et al., A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure. PLoS One. 2014;9(2):e88714
All references(113)
Other
accession IDs
MGD-MRK-14615, MGD-MRK-16618, MGI:99831

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory