Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables interleukin-33 binding activity. Involved in several processes, including macrophage differentiation; positive regulation of macrophage activation; and regulation of cytokine production. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; immune system; musculoskeletal system; skin; and visual system. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1).