Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFT81
  • Mouse genes Ift81
  • Rat genes Ift81
  • Zfish genes ift81
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ift81

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IFT81	IPI	UniProtKB:Q96LB3	Human	PMID:28428259
Molecular Function	GO:0005515	protein binding	IFT81	IPI	UniProtKB:Q9UNT1	Human	PMID:28428259
Molecular Function	GO:0005515	protein binding	IFT81	IPI	UniProtKB:Q96LB3	Human	PMID:28625565
Molecular Function	GO:0005515	protein binding	IFT81	IPI	UniProtKB:Q9UNT1	Human	PMID:28625565
Molecular Function	GO:0005515	protein binding	Ift81	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0015631	tubulin binding	IFT81	IDA		Human	PMID:23990561
Cellular Component	GO:0005814	centriole	Ift81	IDA		Mouse	PMID:29038301
Cellular Component	GO:0005813	centrosome	Ift81	IDA		Mouse	PMID:19253336
Cellular Component	GO:0036064	ciliary basal body	IFT81	IDA		Human	PMID:23990561
Cellular Component	GO:0005929	cilium	Ift81	IDA		Mouse	PMID:19253336
Cellular Component	GO:0005737	cytoplasm	Ift81	IDA		Mouse	MGI:MGI:6445309|PMID:32233951
Cellular Component	GO:0030992	intraciliary transport particle B	IFT81	IPI		Human	PMID:26980730
Cellular Component	GO:0030992	intraciliary transport particle B	Ift81	IDA		Mouse	MGI:MGI:5607391|PMID:24596149
Cellular Component	GO:0030992	intraciliary transport particle B	Ift81	IDA		Mouse	MGI:MGI:5613829|PMID:25443296
Cellular Component	GO:0030992	intraciliary transport particle B	Ift81	IDA		Mouse	PMID:19253336
Cellular Component	GO:0030992	intraciliary transport particle B	Ift81	IDA		Mouse	PMID:23055941
Cellular Component	GO:0030992	intraciliary transport particle B	Ift81	IDA		Mouse	PMID:23810713
Cellular Component	GO:0097225	sperm midpiece	Ift81	IDA		Mouse	PMID:23055941
Cellular Component	GO:0097228	sperm principal piece	Ift81	IDA		Mouse	PMID:23055941
Biological Process	GO:0060271	cilium assembly	IFT81	IMP		Human	PMID:23990561
Biological Process	GO:0060271	cilium assembly	IFT81	IMP		Human	PMID:27666822
Biological Process	GO:0035735	intraciliary transport involved in cilium assembly	IFT81	IMP		Human	PMID:23990561
Biological Process	GO:0048793	pronephros development	ift81	IGI	ZFIN:ZDB-MRPHLNO-090428-5,ZFIN:ZDB-MRPHLNO-090428-7	Zfish	PMID:19008302
Biological Process	GO:0008589	regulation of smoothened signaling pathway	IFT81	IMP		Human	PMID:27666822
Biological Process	GO:0032006	regulation of TOR signaling	ift81	IMP	ZFIN:ZDB-GENO-090429-2	Zfish	PMID:19008302
Biological Process	GO:0120316	sperm flagellum assembly	Ift81	IMP		Mouse	MGI:MGI:6445309|PMID:32233951
Biological Process	GO:0007283	spermatogenesis	Ift81	IEP		Mouse	MGI:MGI:2450080|PMID:12549821
Biological Process	GO:0007283	spermatogenesis	Ift81	IMP		Mouse	MGI:MGI:6445309|PMID:32233951

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern