Gene_Ontology
        biological_process
                biological regulation
                        regulation of biological process
                                regulation of cellular process
                                        regulation of cell communication
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                biological regulation
                        regulation of biological process
                                regulation of cellular process
                                        signal transduction
                                                cell surface receptor signaling pathway
                                                        smoothened signaling pathway
                                                                ciliary receptor clustering involved in smoothened signaling pathway
                                                                mesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                        negative regulation of smoothened signaling pathway +
                                                                        positive regulation of smoothened signaling pathway +
                                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                signal transduction downstream of smoothened +
                                                                smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                smoothened signaling pathway involved in lung development
                                                                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                biological regulation
                        regulation of biological process
                                regulation of cellular process
                                        signal transduction
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                biological regulation
                        regulation of biological process
                                regulation of response to stimulus
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                biological regulation
                        regulation of biological process
                                regulation of signaling
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                cellular process
                        regulation of cellular process
                                regulation of cell communication
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                cellular process
                        regulation of cellular process
                                signal transduction
                                        cell surface receptor signaling pathway
                                                smoothened signaling pathway
                                                        ciliary receptor clustering involved in smoothened signaling pathway
                                                        mesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        signal transduction downstream of smoothened +
                                                        smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        smoothened signaling pathway involved in lung development
                                                        smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                cellular process
                        regulation of cellular process
                                signal transduction
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                cellular process
                        single-organism cellular process
                                cell communication
                                        regulation of cell communication
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                cellular process
                        single-organism cellular process
                                cell communication
                                        signal transduction
                                                cell surface receptor signaling pathway
                                                        smoothened signaling pathway
                                                                ciliary receptor clustering involved in smoothened signaling pathway
                                                                mesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                        negative regulation of smoothened signaling pathway +
                                                                        positive regulation of smoothened signaling pathway +
                                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                signal transduction downstream of smoothened +
                                                                smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                smoothened signaling pathway involved in lung development
                                                                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                cellular process
                        single-organism cellular process
                                cell communication
                                        signal transduction
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                cellular process
                        single-organism cellular process
                                cellular response to stimulus
                                        signal transduction
                                                cell surface receptor signaling pathway
                                                        smoothened signaling pathway
                                                                ciliary receptor clustering involved in smoothened signaling pathway
                                                                mesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                        negative regulation of smoothened signaling pathway +
                                                                        positive regulation of smoothened signaling pathway +
                                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                signal transduction downstream of smoothened +
                                                                smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                smoothened signaling pathway involved in lung development
                                                                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                cellular process
                        single-organism cellular process
                                cellular response to stimulus
                                        signal transduction
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                regulation of biological process
                        regulation of cellular process
                                regulation of cell communication
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                regulation of biological process
                        regulation of cellular process
                                signal transduction
                                        cell surface receptor signaling pathway
                                                smoothened signaling pathway
                                                        ciliary receptor clustering involved in smoothened signaling pathway
                                                        mesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        signal transduction downstream of smoothened +
                                                        smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        smoothened signaling pathway involved in lung development
                                                        smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                regulation of biological process
                        regulation of cellular process
                                signal transduction
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                regulation of biological process
                        regulation of response to stimulus
                                regulation of signal transduction
                                        adaptation of signaling pathway +
                                        extracellular regulation of signal transduction +
                                        modulation of signal transduction in other organism +
                                        negative regulation of signal transduction +
                                        positive regulation of signal transduction +
                                        regulation of abscisic acid mediated signaling pathway +
                                        regulation of antigen receptor-mediated signaling pathway +
                                        regulation of apoptotic signaling pathway +
                                        regulation of auxin mediated signaling pathway +
                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                        regulation of brassinosteroid mediated signaling pathway +
                                        regulation of calcium-mediated signaling +
                                        regulation of cAMP-mediated signaling +
                                        regulation of CD40 signaling pathway +
                                        regulation of cGMP-mediated signaling +
                                        regulation of cytokine-mediated signaling pathway +
                                        regulation of cytokinin mediated signaling pathway +
                                        regulation of endoplasmic reticulum unfolded protein response +
                                        regulation of ephrin receptor signaling pathway +
                                        regulation of ERBB signaling pathway +
                                        regulation of Fas signaling pathway +
                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                        regulation of fibroblast growth factor receptor signaling pathway +
                                        regulation of G-protein coupled receptor protein signaling pathway +
                                        regulation of gibberellic acid mediated signaling pathway +
                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                        regulation of glucocorticoid mediated signaling pathway +
                                        regulation of glutamate receptor signaling pathway +
                                        regulation of growth hormone receptor signaling pathway +
                                        regulation of hippo signaling cascade +
                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                        regulation of insulin receptor signaling pathway +
                                        regulation of insulin-like growth factor receptor signaling pathway +
                                        regulation of integrin-mediated signaling pathway +
                                        regulation of intracellular protein kinase cascade +
                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                        regulation of jasmonic acid mediated signaling pathway
                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                        regulation of neurotrophin TRK receptor signaling pathway +
                                        regulation of NIK/NF-kappaB cascade +
                                        regulation of nitric oxide mediated signal transduction +
                                        regulation of Notch signaling pathway +
                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                        regulation of peptidoglycan recognition protein signaling pathway +
                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                        regulation of phosphatidylinositol 3-kinase cascade +
                                        regulation of phosphorelay signal transduction system +
                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                        regulation of receptor activity +
                                        regulation of red or far-red light signaling pathway +
                                        regulation of retinoic acid receptor signaling pathway +
                                        regulation of Roundabout signaling pathway +
                                        regulation of salicylic acid mediated signaling pathway +
                                        regulation of semaphorin-plexin signaling pathway +
                                        regulation of sevenless signaling pathway +
                                        regulation of signal transduction by p53 class mediator +
                                        regulation of signal transduction by receptor internalization +
                                        regulation of signal transduction in response to host +
                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                        regulation of small GTPase mediated signal transduction +
                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                negative regulation of smoothened signaling pathway +
                                                positive regulation of smoothened signaling pathway +
                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                        regulation of sphingolipid mediated signaling pathway +
                                        regulation of SREBP signaling pathway +
                                        regulation of thyroid hormone mediated signaling pathway +
                                        regulation of Toll signaling pathway +
                                        regulation of toll-like receptor signaling pathway +
                                        regulation of TOR signaling cascade +
                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                        regulation of vascular endothelial growth factor signaling pathway +
                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                        regulation of vitamin D receptor signaling pathway +
                                        regulation of Wnt receptor signaling pathway +
                                        signal complex assembly

---

Gene_Ontology
        biological_process
                regulation of biological process
                        regulation of signaling
                                regulation of signal transduction
                                        adaptation of signaling pathway +
                                        extracellular regulation of signal transduction +
                                        modulation of signal transduction in other organism +
                                        negative regulation of signal transduction +
                                        positive regulation of signal transduction +
                                        regulation of abscisic acid mediated signaling pathway +
                                        regulation of antigen receptor-mediated signaling pathway +
                                        regulation of apoptotic signaling pathway +
                                        regulation of auxin mediated signaling pathway +
                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                        regulation of brassinosteroid mediated signaling pathway +
                                        regulation of calcium-mediated signaling +
                                        regulation of cAMP-mediated signaling +
                                        regulation of CD40 signaling pathway +
                                        regulation of cGMP-mediated signaling +
                                        regulation of cytokine-mediated signaling pathway +
                                        regulation of cytokinin mediated signaling pathway +
                                        regulation of endoplasmic reticulum unfolded protein response +
                                        regulation of ephrin receptor signaling pathway +
                                        regulation of ERBB signaling pathway +
                                        regulation of Fas signaling pathway +
                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                        regulation of fibroblast growth factor receptor signaling pathway +
                                        regulation of G-protein coupled receptor protein signaling pathway +
                                        regulation of gibberellic acid mediated signaling pathway +
                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                        regulation of glucocorticoid mediated signaling pathway +
                                        regulation of glutamate receptor signaling pathway +
                                        regulation of growth hormone receptor signaling pathway +
                                        regulation of hippo signaling cascade +
                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                        regulation of insulin receptor signaling pathway +
                                        regulation of insulin-like growth factor receptor signaling pathway +
                                        regulation of integrin-mediated signaling pathway +
                                        regulation of intracellular protein kinase cascade +
                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                        regulation of jasmonic acid mediated signaling pathway
                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                        regulation of neurotrophin TRK receptor signaling pathway +
                                        regulation of NIK/NF-kappaB cascade +
                                        regulation of nitric oxide mediated signal transduction +
                                        regulation of Notch signaling pathway +
                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                        regulation of peptidoglycan recognition protein signaling pathway +
                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                        regulation of phosphatidylinositol 3-kinase cascade +
                                        regulation of phosphorelay signal transduction system +
                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                        regulation of receptor activity +
                                        regulation of red or far-red light signaling pathway +
                                        regulation of retinoic acid receptor signaling pathway +
                                        regulation of Roundabout signaling pathway +
                                        regulation of salicylic acid mediated signaling pathway +
                                        regulation of semaphorin-plexin signaling pathway +
                                        regulation of sevenless signaling pathway +
                                        regulation of signal transduction by p53 class mediator +
                                        regulation of signal transduction by receptor internalization +
                                        regulation of signal transduction in response to host +
                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                        regulation of small GTPase mediated signal transduction +
                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                negative regulation of smoothened signaling pathway +
                                                positive regulation of smoothened signaling pathway +
                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                        regulation of sphingolipid mediated signaling pathway +
                                        regulation of SREBP signaling pathway +
                                        regulation of thyroid hormone mediated signaling pathway +
                                        regulation of Toll signaling pathway +
                                        regulation of toll-like receptor signaling pathway +
                                        regulation of TOR signaling cascade +
                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                        regulation of vascular endothelial growth factor signaling pathway +
                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                        regulation of vitamin D receptor signaling pathway +
                                        regulation of Wnt receptor signaling pathway +
                                        signal complex assembly

---

Gene_Ontology
        biological_process
                response to stimulus
                        cellular response to stimulus
                                signal transduction
                                        cell surface receptor signaling pathway
                                                smoothened signaling pathway
                                                        ciliary receptor clustering involved in smoothened signaling pathway
                                                        mesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        signal transduction downstream of smoothened +
                                                        smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        smoothened signaling pathway involved in lung development
                                                        smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                response to stimulus
                        cellular response to stimulus
                                signal transduction
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                response to stimulus
                        regulation of response to stimulus
                                regulation of signal transduction
                                        adaptation of signaling pathway +
                                        extracellular regulation of signal transduction +
                                        modulation of signal transduction in other organism +
                                        negative regulation of signal transduction +
                                        positive regulation of signal transduction +
                                        regulation of abscisic acid mediated signaling pathway +
                                        regulation of antigen receptor-mediated signaling pathway +
                                        regulation of apoptotic signaling pathway +
                                        regulation of auxin mediated signaling pathway +
                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                        regulation of brassinosteroid mediated signaling pathway +
                                        regulation of calcium-mediated signaling +
                                        regulation of cAMP-mediated signaling +
                                        regulation of CD40 signaling pathway +
                                        regulation of cGMP-mediated signaling +
                                        regulation of cytokine-mediated signaling pathway +
                                        regulation of cytokinin mediated signaling pathway +
                                        regulation of endoplasmic reticulum unfolded protein response +
                                        regulation of ephrin receptor signaling pathway +
                                        regulation of ERBB signaling pathway +
                                        regulation of Fas signaling pathway +
                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                        regulation of fibroblast growth factor receptor signaling pathway +
                                        regulation of G-protein coupled receptor protein signaling pathway +
                                        regulation of gibberellic acid mediated signaling pathway +
                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                        regulation of glucocorticoid mediated signaling pathway +
                                        regulation of glutamate receptor signaling pathway +
                                        regulation of growth hormone receptor signaling pathway +
                                        regulation of hippo signaling cascade +
                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                        regulation of insulin receptor signaling pathway +
                                        regulation of insulin-like growth factor receptor signaling pathway +
                                        regulation of integrin-mediated signaling pathway +
                                        regulation of intracellular protein kinase cascade +
                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                        regulation of jasmonic acid mediated signaling pathway
                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                        regulation of neurotrophin TRK receptor signaling pathway +
                                        regulation of NIK/NF-kappaB cascade +
                                        regulation of nitric oxide mediated signal transduction +
                                        regulation of Notch signaling pathway +
                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                        regulation of peptidoglycan recognition protein signaling pathway +
                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                        regulation of phosphatidylinositol 3-kinase cascade +
                                        regulation of phosphorelay signal transduction system +
                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                        regulation of receptor activity +
                                        regulation of red or far-red light signaling pathway +
                                        regulation of retinoic acid receptor signaling pathway +
                                        regulation of Roundabout signaling pathway +
                                        regulation of salicylic acid mediated signaling pathway +
                                        regulation of semaphorin-plexin signaling pathway +
                                        regulation of sevenless signaling pathway +
                                        regulation of signal transduction by p53 class mediator +
                                        regulation of signal transduction by receptor internalization +
                                        regulation of signal transduction in response to host +
                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                        regulation of small GTPase mediated signal transduction +
                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                negative regulation of smoothened signaling pathway +
                                                positive regulation of smoothened signaling pathway +
                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                        regulation of sphingolipid mediated signaling pathway +
                                        regulation of SREBP signaling pathway +
                                        regulation of thyroid hormone mediated signaling pathway +
                                        regulation of Toll signaling pathway +
                                        regulation of toll-like receptor signaling pathway +
                                        regulation of TOR signaling cascade +
                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                        regulation of vascular endothelial growth factor signaling pathway +
                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                        regulation of vitamin D receptor signaling pathway +
                                        regulation of Wnt receptor signaling pathway +
                                        signal complex assembly

---

Gene_Ontology
        biological_process
                signaling
                        single organism signaling
                                regulation of signaling
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                signaling
                        single organism signaling
                                signal transduction
                                        cell surface receptor signaling pathway
                                                smoothened signaling pathway
                                                        ciliary receptor clustering involved in smoothened signaling pathway
                                                        mesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        signal transduction downstream of smoothened +
                                                        smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        smoothened signaling pathway involved in lung development
                                                        smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                signaling
                        single organism signaling
                                signal transduction
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                single-organism process
                        single organism signaling
                                regulation of signaling
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                single-organism process
                        single organism signaling
                                signal transduction
                                        cell surface receptor signaling pathway
                                                smoothened signaling pathway
                                                        ciliary receptor clustering involved in smoothened signaling pathway
                                                        mesenchymal smoothened signaling pathway involved in prostate gland development
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        signal transduction downstream of smoothened +
                                                        smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                        smoothened signaling pathway involved in lung development
                                                        smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                        smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                        smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                single-organism process
                        single organism signaling
                                signal transduction
                                        regulation of signal transduction
                                                adaptation of signaling pathway +
                                                extracellular regulation of signal transduction +
                                                modulation of signal transduction in other organism +
                                                negative regulation of signal transduction +
                                                positive regulation of signal transduction +
                                                regulation of abscisic acid mediated signaling pathway +
                                                regulation of antigen receptor-mediated signaling pathway +
                                                regulation of apoptotic signaling pathway +
                                                regulation of auxin mediated signaling pathway +
                                                regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                regulation of brassinosteroid mediated signaling pathway +
                                                regulation of calcium-mediated signaling +
                                                regulation of cAMP-mediated signaling +
                                                regulation of CD40 signaling pathway +
                                                regulation of cGMP-mediated signaling +
                                                regulation of cytokine-mediated signaling pathway +
                                                regulation of cytokinin mediated signaling pathway +
                                                regulation of endoplasmic reticulum unfolded protein response +
                                                regulation of ephrin receptor signaling pathway +
                                                regulation of ERBB signaling pathway +
                                                regulation of Fas signaling pathway +
                                                regulation of Fc receptor mediated stimulatory signaling pathway +
                                                regulation of fibroblast growth factor receptor signaling pathway +
                                                regulation of G-protein coupled receptor protein signaling pathway +
                                                regulation of gibberellic acid mediated signaling pathway +
                                                regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                regulation of glucocorticoid mediated signaling pathway +
                                                regulation of glutamate receptor signaling pathway +
                                                regulation of growth hormone receptor signaling pathway +
                                                regulation of hippo signaling cascade +
                                                regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                regulation of insulin receptor signaling pathway +
                                                regulation of insulin-like growth factor receptor signaling pathway +
                                                regulation of integrin-mediated signaling pathway +
                                                regulation of intracellular protein kinase cascade +
                                                regulation of intracellular steroid hormone receptor signaling pathway +
                                                regulation of jasmonic acid mediated signaling pathway
                                                regulation of lipopolysaccharide-mediated signaling pathway +
                                                regulation of neurotrophin TRK receptor signaling pathway +
                                                regulation of NIK/NF-kappaB cascade +
                                                regulation of nitric oxide mediated signal transduction +
                                                regulation of Notch signaling pathway +
                                                regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                regulation of peptidoglycan recognition protein signaling pathway +
                                                regulation of peroxisome proliferator activated receptor signaling pathway +
                                                regulation of phosphatidylinositol 3-kinase cascade +
                                                regulation of phosphorelay signal transduction system +
                                                regulation of platelet-derived growth factor receptor signaling pathway +
                                                regulation of receptor activity +
                                                regulation of red or far-red light signaling pathway +
                                                regulation of retinoic acid receptor signaling pathway +
                                                regulation of Roundabout signaling pathway +
                                                regulation of salicylic acid mediated signaling pathway +
                                                regulation of semaphorin-plexin signaling pathway +
                                                regulation of sevenless signaling pathway +
                                                regulation of signal transduction by p53 class mediator +
                                                regulation of signal transduction by receptor internalization +
                                                regulation of signal transduction in response to host +
                                                regulation of signal transduction involved in conjugation with cellular fusion +
                                                regulation of small GTPase mediated signal transduction +
                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                        negative regulation of smoothened signaling pathway +
                                                        positive regulation of smoothened signaling pathway +
                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                regulation of sphingolipid mediated signaling pathway +
                                                regulation of SREBP signaling pathway +
                                                regulation of thyroid hormone mediated signaling pathway +
                                                regulation of Toll signaling pathway +
                                                regulation of toll-like receptor signaling pathway +
                                                regulation of TOR signaling cascade +
                                                regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                regulation of vascular endothelial growth factor receptor signaling pathway +
                                                regulation of vascular endothelial growth factor signaling pathway +
                                                regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                regulation of vitamin D receptor signaling pathway +
                                                regulation of Wnt receptor signaling pathway +
                                                signal complex assembly

---

Gene_Ontology
        biological_process
                single-organism process
                        single-organism cellular process
                                cell communication
                                        regulation of cell communication
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                single-organism process
                        single-organism cellular process
                                cell communication
                                        signal transduction
                                                cell surface receptor signaling pathway
                                                        smoothened signaling pathway
                                                                ciliary receptor clustering involved in smoothened signaling pathway
                                                                mesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                        negative regulation of smoothened signaling pathway +
                                                                        positive regulation of smoothened signaling pathway +
                                                                        regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                signal transduction downstream of smoothened +
                                                                smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                                smoothened signaling pathway involved in growth plate cartilage chondrocyte development
                                                                smoothened signaling pathway involved in lung development
                                                                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
                                                                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
                                                                smoothened signaling pathway involved in ventral spinal cord patterning +

---

Gene_Ontology
        biological_process
                single-organism process
                        single-organism cellular process
                                cell communication
                                        signal transduction
                                                regulation of signal transduction
                                                        adaptation of signaling pathway +
                                                        extracellular regulation of signal transduction +
                                                        modulation of signal transduction in other organism +
                                                        negative regulation of signal transduction +
                                                        positive regulation of signal transduction +
                                                        regulation of abscisic acid mediated signaling pathway +
                                                        regulation of antigen receptor-mediated signaling pathway +
                                                        regulation of apoptotic signaling pathway +
                                                        regulation of auxin mediated signaling pathway +
                                                        regulation of brain-derived neurotrophic factor receptor signaling pathway +
                                                        regulation of brassinosteroid mediated signaling pathway +
                                                        regulation of calcium-mediated signaling +
                                                        regulation of cAMP-mediated signaling +
                                                        regulation of CD40 signaling pathway +
                                                        regulation of cGMP-mediated signaling +
                                                        regulation of cytokine-mediated signaling pathway +
                                                        regulation of cytokinin mediated signaling pathway +
                                                        regulation of endoplasmic reticulum unfolded protein response +
                                                        regulation of ephrin receptor signaling pathway +
                                                        regulation of ERBB signaling pathway +
                                                        regulation of Fas signaling pathway +
                                                        regulation of Fc receptor mediated stimulatory signaling pathway +
                                                        regulation of fibroblast growth factor receptor signaling pathway +
                                                        regulation of G-protein coupled receptor protein signaling pathway +
                                                        regulation of gibberellic acid mediated signaling pathway +
                                                        regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation +
                                                        regulation of glucocorticoid mediated signaling pathway +
                                                        regulation of glutamate receptor signaling pathway +
                                                        regulation of growth hormone receptor signaling pathway +
                                                        regulation of hippo signaling cascade +
                                                        regulation of hypoxia-inducible factor-1alpha signaling pathway +
                                                        regulation of insulin receptor signaling pathway +
                                                        regulation of insulin-like growth factor receptor signaling pathway +
                                                        regulation of integrin-mediated signaling pathway +
                                                        regulation of intracellular protein kinase cascade +
                                                        regulation of intracellular steroid hormone receptor signaling pathway +
                                                        regulation of jasmonic acid mediated signaling pathway
                                                        regulation of lipopolysaccharide-mediated signaling pathway +
                                                        regulation of neurotrophin TRK receptor signaling pathway +
                                                        regulation of NIK/NF-kappaB cascade +
                                                        regulation of nitric oxide mediated signal transduction +
                                                        regulation of Notch signaling pathway +
                                                        regulation of nucleotide-binding oligomerization domain containing signaling pathway +
                                                        regulation of peptidoglycan recognition protein signaling pathway +
                                                        regulation of peroxisome proliferator activated receptor signaling pathway +
                                                        regulation of phosphatidylinositol 3-kinase cascade +
                                                        regulation of phosphorelay signal transduction system +
                                                        regulation of platelet-derived growth factor receptor signaling pathway +
                                                        regulation of receptor activity +
                                                        regulation of red or far-red light signaling pathway +
                                                        regulation of retinoic acid receptor signaling pathway +
                                                        regulation of Roundabout signaling pathway +
                                                        regulation of salicylic acid mediated signaling pathway +
                                                        regulation of semaphorin-plexin signaling pathway +
                                                        regulation of sevenless signaling pathway +
                                                        regulation of signal transduction by p53 class mediator +
                                                        regulation of signal transduction by receptor internalization +
                                                        regulation of signal transduction in response to host +
                                                        regulation of signal transduction involved in conjugation with cellular fusion +
                                                        regulation of small GTPase mediated signal transduction +
                                                        regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning +
                                                        regulation of sphingolipid mediated signaling pathway +
                                                        regulation of SREBP signaling pathway +
                                                        regulation of thyroid hormone mediated signaling pathway +
                                                        regulation of Toll signaling pathway +
                                                        regulation of toll-like receptor signaling pathway +
                                                        regulation of TOR signaling cascade +
                                                        regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                        regulation of vascular endothelial growth factor receptor signaling pathway +
                                                        regulation of vascular endothelial growth factor signaling pathway +
                                                        regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway +
                                                        regulation of vitamin D receptor signaling pathway +
                                                        regulation of Wnt receptor signaling pathway +
                                                        signal complex assembly

---

Gene_Ontology
        biological_process
                single-organism process
                        single-organism cellular process
                                cellular response to stimulus
                                        signal transduction
                                                cell surface receptor signaling pathway
                                                        smoothened signaling pathway
                                                                ciliary receptor clustering involved in smoothened signaling pathway
                                                                mesenchymal smoothened signaling pathway involved in prostate gland development
                                                                negative regulation of smoothened signaling pathway +
                                                                positive regulation of smoothened signaling pathway +
                                                                regulation of smoothened signaling pathway [GO:0008589] (46 genes, 66 annotations)
                                                                        negative regulation of smoothened signaling pathway +