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Ift81 Gene Detail
Summary
  • Symbol
    Ift81
  • Name
    intraflagellar transport 81
  • Synonyms
    Cdv1, CDV-1R
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098597
    NCBI Gene: 12589
  • Gene Overview
    MyGene.info: IFT81
Location & Maps
more
  • Sequence Map
    Chr5:122550204-122614518 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      64315 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 62.44 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    IFT81, intraflagellar transport 81
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IFT81, intraflagellar transport 81
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDV1, CDV-1, CDV1R, CDV-1R, DV1
  • Links
    NCBI Gene ID: 28981
    neXtProt AC: NX_Q8WYA0

  • Chr Location
    12q24.13; chr12:110124335-110218795 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 7664
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: IFT81
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Ift81
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026713 VEGA Gene Model | MGI Sequence Detail 64315 C57BL/6J ±  kb
transcript OTTMUST00000066092 VEGA | MGI Sequence Detail 2950 Not Applicable  
polypeptide OTTMUSP00000033053 VEGA | MGI Sequence Detail 676 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    360 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000008939 intraflagellar transport protein 81
  • InterPro Domains
    IPR029600 Intraflagellar transport protein 81
Molecular
Reagents
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  • All nucleic 45
    cDNA 45

    Microarray probesets 6
Other
Accession IDs
less
MGI:2141144
References
more
  • Summaries
    All 38
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:40593 Masuda M, et al., A novel gene suppressed in the ventricle of carnitine-deficient juvenile visceral steatosis mice. FEBS Lett. 1997 May 19;408(2):221-4
  • Latest
    J:217382 Liew GM, et al., The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3. Dev Cell. 2014 Nov 10;31(3):265-78

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory