Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IFI35
  • Mouse genes Ifi35
  • Rat genes Ifi35
  • Zfish genes ifi35
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ifi35

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	IFI35	IDA		Human	PMID:10950963
Molecular Function	GO:0005515	protein binding	IFI35	IPI	UniProtKB:Q13287	Human	PMID:10779520
Molecular Function	GO:0005515	protein binding	IFI35	IPI	UniProtKB:Q13287	Human	PMID:10950963
Molecular Function	GO:0005515	protein binding	IFI35	IPI	UniProtKB:Q6UXB4	Human	PMID:18624398
Molecular Function	GO:0005515	protein binding	IFI35	IPI	UniProtKB:Q13287	Human	PMID:26342464
Molecular Function	GO:0005515	protein binding	IFI35	IPI	UniProtKB:Q16520	Human	PMID:8954125
Cellular Component	GO:0005737	cytoplasm	IFI35	IDA		Human	PMID:10950963
Cellular Component	GO:0005829	cytosol	IFI35	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	IFI35	IDA		Human	PMID:10779520
Cellular Component	GO:0005829	cytosol	IFI35	IDA		Human	PMID:10950963
Cellular Component	GO:0005615	extracellular space	IFI35	IDA		Human	PMID:29038465
Cellular Component	GO:0005615	extracellular space	Ifi35	IDA		Mouse	MGI:MGI:6099204|PMID:29038465
Cellular Component	GO:0016020	membrane	IFI35	IDA		Human	PMID:10950963
Cellular Component	GO:0005730	nucleolus	IFI35	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	IFI35	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	IFI35	IDA		Human	PMID:10950963
Cellular Component	GO:0005634	nucleus	IFI35	IDA		Human	PMID:8288566
Biological Process	GO:0002281	macrophage activation involved in immune response	IFI35	IDA		Human	PMID:29038465
Biological Process	GO:0008285	negative regulation of cell population proliferation	IFI35	IMP		Human	PMID:29350881
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	IFI35	IMP		Human	PMID:29350881
Biological Process	GO:0050729	positive regulation of inflammatory response	IFI35	IDA		Human	PMID:29038465
Biological Process	GO:0050729	positive regulation of inflammatory response	Ifi35	IMP		Mouse	MGI:MGI:6099204|PMID:29038465
Biological Process	GO:0045089	positive regulation of innate immune response	IFI35	IDA		Human	PMID:29038465
Biological Process	GO:0045089	positive regulation of innate immune response	Ifi35	IMP		Mouse	MGI:MGI:6099204|PMID:29038465
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Ifi35	IMP		Mouse	MGI:MGI:6099204|PMID:29038465
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	IFI35	IDA		Human	PMID:29038465

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern