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Ifi35 Gene Detail
Summary
  • Symbol
    Ifi35
  • Name
    interferon-induced protein 35
  • Synonyms
    2010008K16Rik, IFP35
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917360
    NCBI Gene: 70110
  • Gene Overview
    MyGene.info: IFI35
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:101448412-101458701 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 65.07 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    79 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917360
protein coding gene Chr11:101448407-101458701 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019203
protein coding gene Chr11:104315936-104326725 (+)
A/J MGP_AJ_G0019171
protein coding gene Chr11:99930226-99940526 (+)
AKR/J MGP_AKRJ_G0019140
protein coding gene Chr11:103036744-103047031 (+)
BALB/cJ MGP_BALBcJ_G0019145
protein coding gene Chr11:100422709-100432986 (+)
C3H/HeJ MGP_C3HHeJ_G0018954
protein coding gene Chr11:103211524-103223585 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019594
protein coding gene Chr11:107591139-107601379 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017220
protein coding gene Chr11:97327228-97338308 (+)
CAST/EiJ MGP_CASTEiJ_G0018508
protein coding gene Chr11:104191906-104202266 (+)
CBA/J MGP_CBAJ_G0018923
protein coding gene Chr11:112018497-112029933 (+)
DBA/2J MGP_DBA2J_G0019035
protein coding gene Chr11:99451702-99462546 (+)
FVB/NJ MGP_FVBNJ_G0019025
protein coding gene Chr11:98994933-99004890 (+)
LP/J MGP_LPJ_G0019104
protein coding gene Chr11:104856002-104866304 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019056
protein coding gene Chr11:111575665-111585865 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019632
protein coding gene Chr11:103366471-103376658 (+)
PWK/PhJ MGP_PWKPhJ_G0018271
protein coding gene Chr11:100513947-100524801 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018063
protein coding gene Chr11:103088788-103100031 (+)
WSB/EiJ MGP_WSBEiJ_G0018557
protein coding gene Chr11:103361716-103371977 (+)



Homology
more
  • Human Ortholog
    IFI35, interferon induced protein 35
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IFI35, interferon induced protein 35
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IFP35
  • Links
    NCBI Gene ID: 3430
    neXtProt AC: NX_P80217
    UniProt: P80217

  • Chr Location
    17q21.31; chr17:43006725-43014459 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70110 NCBI Gene Model | MGI Sequence Detail 10290 C57BL/6J ±  kb
transcript NM_027320 RefSeq | MGI Sequence Detail 1360 C57BL/6  
polypeptide Q9D8C4 UniProt | EBI | MGI Sequence Detail 286 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 75

    Microarray probesets 5
Other
Accession IDs
less
MGI:2144592
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:264214 Gounder AP, et al., Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer. PLoS Pathog. 2018 Apr;14(4):e1007001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory