Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HYAL3
  • Mouse genes Hyal3
  • Rat genes Hyal3
  • Zfish genes hyal3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hyal3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033906	hyaluronoglucuronidase activity	HYAL3	IDA		Human	PMID:21699545
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL3	IDA		Human	PMID:11944887
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL3	IDA		Human	PMID:17170110
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	HYAL3	IDA		Human	PMID:18390475
Molecular Function	GO:0004415	hyalurononglucosaminidase activity	Hyal3	IDA		Mouse	MGI:MGI:4834982|PMID:20586096
Molecular Function	GO:0005515	protein binding	HYAL3	IPI	UniProtKB:O75553	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HYAL3	IPI	UniProtKB:Q8N9W6-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HYAL3	IPI	UniProtKB:Q9UQM7	Human	PMID:32296183
Cellular Component	GO:0002080	acrosomal membrane	Hyal3	IDA		Mouse	MGI:MGI:4834982|PMID:20586096
Cellular Component	GO:0001669	acrosomal vesicle	Hyal3	IDA		Mouse	MGI:MGI:4834982|PMID:20586096
Cellular Component	GO:0031410	cytoplasmic vesicle	HYAL3	IDA		Human	PMID:18390475
Cellular Component	GO:0031410	cytoplasmic vesicle	Hyal3	IDA		Mouse	MGI:MGI:6094642|PMID:18234732
Cellular Component	GO:0005769	early endosome	Hyal3	IDA		Mouse	MGI:MGI:6094642|PMID:18234732
Cellular Component	GO:0005783	endoplasmic reticulum	Hyal3	IDA		Mouse	MGI:MGI:6094642|PMID:18234732
Cellular Component	GO:0005764	lysosome	HYAL3	IDA		Human	PMID:16600643
Cellular Component	GO:0097225	sperm midpiece	Hyal3	IDA		Mouse	MGI:MGI:4834982|PMID:20586096
Biological Process	GO:0051216	cartilage development	HYAL3	IEP		Human	PMID:11944887
Biological Process	GO:0071347	cellular response to interleukin-1	HYAL3	IDA		Human	PMID:18390475
Biological Process	GO:0071356	cellular response to tumor necrosis factor	HYAL3	IEP		Human	PMID:18390475
Biological Process	GO:0071493	cellular response to UV-B	HYAL3	IDA		Human	PMID:21699545
Biological Process	GO:0030214	hyaluronan catabolic process	HYAL3	IDA		Human	PMID:21699545
Biological Process	GO:0030214	hyaluronan catabolic process	Hyal3	IDA		Mouse	MGI:MGI:4834982|PMID:20586096
Biological Process	GO:0006954	inflammatory response	HYAL3	IDA		Human	PMID:18390475
Biological Process	GO:2000355	negative regulation of ovarian follicle development	Hyal3	IDA		Mouse	MGI:MGI:6094534|PMID:18653706
Biological Process	GO:0001552	ovarian follicle atresia	Hyal3	IDA		Mouse	MGI:MGI:6094534|PMID:18653706
Biological Process	GO:0007341	penetration of zona pellucida	Hyal3	IMP		Mouse	MGI:MGI:4834982|PMID:20586096
Biological Process	GO:2000368	positive regulation of acrosomal vesicle exocytosis	Hyal3	IMP		Mouse	MGI:MGI:4834982|PMID:20586096
Biological Process	GO:0046677	response to antibiotic	HYAL3	IEP		Human	PMID:11944887
Biological Process	GO:0009615	response to virus	HYAL3	IDA		Human	PMID:11296287
Biological Process	GO:0009615	response to virus	Hyal3	IDA		Mouse	MGI:MGI:5315372|PMID:11296287

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern