Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSPB8
  • Mouse genes Hspb8
  • Rat genes Hspb8
  • Zfish genes hspb8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hspb8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	HSPB8	IPI	UniProtKB:Q9UJY1	Human	PMID:14594798
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:P04792	Human	PMID:14594798
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q16082	Human	PMID:14594798
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9UBY9	Human	PMID:14594798
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9UBY9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:18006506
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9UJY1	Human	PMID:18006506
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O75190	Human	PMID:22366786
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q15773	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q15773	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q2TAL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9UBY9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9UNI6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:28144995
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9HC29-1	Human	PMID:31273097
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O14512	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O15375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O75865-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:P49247	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q2TAL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q53TS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q7L5A3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q8IVT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q9UBY9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:O95817	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	HSPB8	IPI	UniProtKB:Q15773	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Hspb8	IPI	PR:Q9JLV1	Mouse	PMID:20060297
Molecular Function	GO:0042803	protein homodimerization activity	HSPB8	IDA		Human	PMID:18006506
Cellular Component	GO:0005737	cytoplasm	HSPB8	IDA		Human	PMID:19464326
Cellular Component	GO:0005737	cytoplasm	HSPB8	IDA		Human	PMID:28144995
Cellular Component	GO:0005829	cytosol	HSPB8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HSPB8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HSPB8	IDA		Human	PMID:19464326
Cellular Component	GO:0101031	protein folding chaperone complex	HSPB8	IDA		Human	PMID:18006506
Biological Process	GO:0034620	cellular response to unfolded protein	HSPB8	IMP		Human	PMID:18006506
Biological Process	GO:1905337	positive regulation of aggrephagy	HSPB8	IMP		Human	PMID:18006506

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern