Hspb8
Gene Detail

Symbol Name ID

Hspb8 heat shock protein 8 MGI:2135756

Synonyms

Cryac, D5Ucla4, E2IG1, H11, H11K, HSP20-like, HSP22

Feature Type

protein coding gene

Genetic Map

Chromosome 5

56.41 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)

Sequence Map

Chr5:116408491-116422864 bp, - strand From VEGA annotation of GRCm38   14374 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:8654  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Sm_HSP_B1
Gene Tree: Hspb8

Human homologs

Human Homolog		HSPB8, heat shock 22kDa protein 8
NCBI Gene ID		26353
neXtProt AC		NX_Q9UJY1
Human Synonyms		CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Human Chr (Location)		12q24.23; chr12:119616595-119632551 (+)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human HSPB8

Alleles and phenotypes

All alleles(16) : Targeted(1) Gene trapped(15)

Gene Ontology (GO) classifications

All GO classifications: (6 annotations)

Process	response to stress
Component	cytoplasm, intracellular, ...
Function	identical protein binding, protein binding

External Resources: FuncBase

Expression

Literature Summary: (9 records)
Data Summary: Results (176)    Tissues (127)    Images (36)
Theiler Stages: 15, 20, 21, 22, 23, 25, 28

Assay Type	Results
Immunohistochemistry	4
RNA in situ	132
Northern blot	40

cDNA source data(132)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(133) cDNA(132) Other(1)
Microarray probesets(6)

Other database links

VEGA Gene Model	OTTMUSG00000014696 (Evidence)
Ensembl Gene Model	ENSMUSG00000041548 (Evidence)
Entrez Gene	80888 (Evidence)
UniGene	21549
DFCI	TC1574577, TC1759947
DoTS	DT.535654, DT.97408252
NIA Mouse Gene Index	U026646
Consensus CDS Project	CCDS19600.1
International Mouse Knockout Project Status	Hspb8

Sequences

Length	Strain/Species
genomic	OTTMUSG00000014696	VEGA Gene Model | MGI Sequence Detail	14374	C57BL/6J
transcript	OTTMUST00000034849	VEGA | MGI Sequence Detail	1816	Not Applicable
polypeptide	OTTMUSP00000015583	VEGA | MGI Sequence Detail	196	Not Applicable

All sequences(37) RefSeq(2) UniProt(1)

Polymorphisms

RFLP(1) : SNPs(93 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001436	Alpha crystallin/Heat shock protein
InterPro	IPR002068	Alpha crystallin/Hsp20 domain
InterPro	IPR008978	HSP20-like chaperone
Protein Ontology	PR:000008820	heat shock protein beta-8

References

(Earliest) J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
(Latest) J:181231 Garcia-Lax N, et al., Developmental expression pattern of hspb8 mRNA in the mouse brain: analysis through online databases. Anat Rec (Hoboken). 2012 Mar;295(3):492-503
All references(55)

Other accession IDs

MGD-MRK-7380, MGI:2141037, MGI:2141190, MGI:93475