Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSD17B7
  • Mouse genes Hsd17b7
  • Rat genes Hsd17b7
  • Zfish genes hsd17b7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd17b7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000253	3-keto sterol reductase activity	HSD17B7	IDA		Human	PMID:12829805
Molecular Function	GO:0000253	3-keto sterol reductase activity	Hsd17b7	IDA		Mouse	PMID:12829805
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	HSD17B7	IDA		Human	PMID:12732193
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	HSD17B7	IDA		Human	PMID:19772289
Molecular Function	GO:0047024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	Hsd17b7	IDA		Mouse	MGI:MGI:2662631|PMID:12732193
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	HSD17B7	IDA		Human	PMID:12732193
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	HSD17B7	IDA		Human	PMID:19772289
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	Hsd17b7	IDA		Mouse	MGI:MGI:2662631|PMID:12732193
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	Hsd17b7	IDA		Mouse	MGI:MGI:1267145|PMID:9658408
Molecular Function	GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)] activity	Hsd17b7	IDA		Rat	PMID:9658408|RGD:30309934
Molecular Function	GO:0005148	prolactin receptor binding	Hsd17b7	IPI	RGD:3407	Rat	PMID:8663045|RGD:69856
Cellular Component	GO:0005783	endoplasmic reticulum	Hsd17b7	IDA		Mouse	PMID:12829805
Cellular Component	GO:0005789	endoplasmic reticulum membrane	HSD17B7	IDA		Human	PMID:12829805
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Hsd17b7	IDA		Mouse	MGI:MGI:2673751|PMID:12829805
Cellular Component	GO:0016020	membrane	Hsd17b7	IDA		Rat	PMID:2318142|RGD:10402363
Biological Process	GO:0008209	androgen metabolic process	HSD17B7	IDA		Human	PMID:12732193
Biological Process	GO:0008209	androgen metabolic process	Hsd17b7	IDA		Mouse	MGI:MGI:2662631|PMID:12732193
Biological Process	GO:0007420	brain development	Hsd17b7	IMP		Mouse	MGI:MGI:3811685|PMID:18669642
Biological Process	GO:0030154	cell differentiation	Hsd17b7	IMP	MGI:5056371	Mouse	PMID:21515572
Biological Process	GO:0006695	cholesterol biosynthetic process	HSD17B7	IDA		Human	PMID:12829805
Biological Process	GO:0006695	cholesterol biosynthetic process	Hsd17b7	IDA		Mouse	PMID:12829805
Biological Process	GO:0048568	embryonic organ development	Hsd17b7	IMP		Mouse	MGI:MGI:3811685|PMID:18669642
Biological Process	GO:0048706	embryonic skeletal system development	Hsd17b7	IMP	MGI:5056371	Mouse	PMID:21515572
Biological Process	GO:0006703	estrogen biosynthetic process	HSD17B7	IDA		Human	PMID:12732193
Biological Process	GO:0006703	estrogen biosynthetic process	Hsd17b7	IDA		Mouse	MGI:MGI:1267145|PMID:9658408
Biological Process	GO:0006703	estrogen biosynthetic process	Hsd17b7	IDA		Mouse	MGI:MGI:2662631|PMID:12732193
Biological Process	GO:0006703	estrogen biosynthetic process	Hsd17b7	IDA		Rat	PMID:9658408|RGD:30309934
Biological Process	GO:0021766	hippocampus development	Hsd17b7	IEP		Rat	PMID:21047951|RGD:4145527
Biological Process	GO:0060135	maternal process involved in female pregnancy	Hsd17b7	IEP		Rat	PMID:9231770|RGD:10402206
Biological Process	GO:0007399	nervous system development	Hsd17b7	IMP	MGI:5056371	Mouse	PMID:21515572
Biological Process	GO:0032355	response to estradiol	Hsd17b7	IEP		Rat	PMID:9231770|RGD:10402206
Biological Process	GO:0014070	response to organic cyclic compound	Hsd17b7	IEP		Rat	PMID:19527300|RGD:2326111
Biological Process	GO:1990637	response to prolactin	Hsd17b7	IEP		Rat	PMID:9231770|RGD:10402206
Biological Process	GO:0009410	response to xenobiotic stimulus	Hsd17b7	IEP		Rat	PMID:9231770|RGD:10402206

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern