Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXB4
  • Mouse genes Hoxb4
  • Rat genes Hoxb4
  • Zfish genes hoxb4a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxb4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Hoxb4	IDA		Mouse	PMID:7911971
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	HOXB4	IDA		Human	PMID:28473536
Cellular Component	GO:0005813	centrosome	HOXB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HOXB4	IDA		Human	GO_REF:0000052
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96188	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96184	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96183	Mouse	PMID:9012503
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96183	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96186	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96189	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96187	Mouse	PMID:10885747
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96176	Mouse	PMID:7628700
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxb4	IGI	MGI:MGI:96190	Mouse	PMID:10885747
Biological Process	GO:0048539	bone marrow development	Hoxb4	IMP	MGI:MGI:3045971	Mouse	PMID:14962901
Biological Process	GO:0060216	definitive hemopoiesis	Hoxb4	IGI	MGI:MGI:96184	Mouse	PMID:17761289
Biological Process	GO:0060216	definitive hemopoiesis	Hoxb4	IGI	MGI:MGI:96180	Mouse	PMID:17761289
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96189	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96186	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96188	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96176	Mouse	PMID:7628700
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96183	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96190	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96187	Mouse	PMID:10885747
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96184	Mouse	PMID:10885747
Biological Process	GO:0060218	hematopoietic stem cell differentiation	HOXB4	IDA		Human	PMID:18932205
Biological Process	GO:0071425	hematopoietic stem cell proliferation	Hoxb4	IMP	MGI:MGI:3045971	Mouse	PMID:14962901
Biological Process	GO:0030097	hemopoiesis	Hoxb4	IMP	MGI:MGI:3045971	Mouse	PMID:14962901
Biological Process	GO:0002011	morphogenesis of an epithelial sheet	Hoxb4	IGI	MGI:MGI:96183	Mouse	PMID:11518511
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hoxb4	IDA		Mouse	PMID:8649375
Biological Process	GO:2000738	positive regulation of stem cell differentiation	HOXB4	IDA		Human	PMID:18932205
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	HOXB4	IDA		Human	PMID:18932205
Biological Process	GO:0048705	skeletal system morphogenesis	Hoxb4	IMP	MGI:MGI:2388364	Mouse	PMID:9012503
Biological Process	GO:0048705	skeletal system morphogenesis	Hoxb4	IGI	MGI:MGI:96183	Mouse	PMID:9012503
Biological Process	GO:0048103	somatic stem cell division	Hoxb4	IDA		Mouse	PMID:12717450
Biological Process	GO:0048536	spleen development	Hoxb4	IMP	MGI:MGI:3045971	Mouse	PMID:14962901

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern