Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HOXA3
  • Mouse genes Hoxa3
  • Rat genes Hoxa3
  • Zfish genes hoxa3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hoxa3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	hoxa3a	IDA		Zfish	PMID:17708765
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Hoxa3	IDA		Mouse	PMID:21170035
Molecular Function	GO:0071837	HMG box domain binding	Hoxa3	IPI	UniProtKB:O55170	Mouse	MGI:MGI:5284787|PMID:16582099
Molecular Function	GO:0005515	protein binding	HOXA3	IPI	UniProtKB:Q15437	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	HOXA3	IPI	UniProtKB:O15145	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOXA3	IPI	UniProtKB:Q15437	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HOXA3	IPI	UniProtKB:O15145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HOXA3	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Cellular Component	GO:0005654	nucleoplasm	HOXA3	IDA		Human	GO_REF:0000052
Biological Process	GO:0001525	angiogenesis	HOXA3	IEP		Human	PMID:17972163
Biological Process	GO:0048645	animal organ formation	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:7635047
Biological Process	GO:0009887	animal organ morphogenesis	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:15100241
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:7913519
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0009952	anterior/posterior pattern specification	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9441667
Biological Process	GO:0001974	blood vessel remodeling	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:15714286
Biological Process	GO:0051216	cartilage development	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0051216	cartilage development	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9441667
Biological Process	GO:0008283	cell population proliferation	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:15714286
Biological Process	GO:0048706	embryonic skeletal system development	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:7913519
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0048704	embryonic skeletal system morphogenesis	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9441667
Biological Process	GO:0010467	gene expression	Hoxa3	IMP	MGI:1889069	Mouse	PMID:19968565
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9441667
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9441667
Biological Process	GO:0021615	glossopharyngeal nerve morphogenesis	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:9441667
Biological Process	GO:0060017	parathyroid gland development	Hoxa3	IGI	MGI:MGI:97485	Mouse	PMID:11476574
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:15714286
Biological Process	GO:0010159	specification of animal organ position	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9520319
Biological Process	GO:0010159	specification of animal organ position	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9520319
Biological Process	GO:0072089	stem cell proliferation	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:15714286
Biological Process	GO:0048538	thymus development	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9520319
Biological Process	GO:0048538	thymus development	Hoxa3	IGI	MGI:MGI:97485	Mouse	PMID:11476574
Biological Process	GO:0048538	thymus development	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:7635047
Biological Process	GO:0048538	thymus development	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9520319
Biological Process	GO:0030878	thyroid gland development	Hoxa3	IGI	MGI:MGI:96184	Mouse	PMID:9524238
Biological Process	GO:0030878	thyroid gland development	Hoxa3	IGI	MGI:MGI:96207	Mouse	PMID:9524238
Biological Process	GO:0030878	thyroid gland development	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:9520319
Biological Process	GO:0030878	thyroid gland development	Hoxa3	IMP	MGI:MGI:1857992	Mouse	PMID:7635047

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern