Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HDAC7
  • Mouse genes Hdac7
  • Rat genes Hdac7
  • Zfish genes hdac7a,hdac7b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hdac7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	HDAC7	IDA		Human	PMID:16980613
Molecular Function	GO:0003682	chromatin binding	Hdac7	IDA		Mouse	PMID:16109736
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HDAC7	IPI	UniProtKB:Q9BZS1	Human	PMID:17360565
Molecular Function	GO:0140297	DNA-binding transcription factor binding	HDAC7	IPI	UniProtKB:Q02078	Human	PMID:20590529
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P08393	Human	PMID:15194749
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P31947	Human	PMID:15778465
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:Q9BZS1-1	Human	PMID:17360565
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:Q9BZS1-2	Human	PMID:17360565
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:Q9BZL6	Human	PMID:17962809
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P31947	Human	PMID:18339811
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P63104	Human	PMID:20224040
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P29590-4	Human	PMID:22155184
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:Q8CFN5	Human	PMID:23565059
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P31947	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P63104	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HDAC7	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	UniProtKB:P62259	Mouse	MGI:MGI:5508292|PMID:11585834
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	UniProtKB:P62259	Mouse	MGI:MGI:5512846|PMID:16956611
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	UniProtKB:Q15139	Mouse	MGI:MGI:6092904|PMID:18509061
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	UniProtKB:P62259	Mouse	MGI:MGI:5508274|PMID:15166223
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	PR:Q60520	Mouse	PMID:10640276
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	PR:Q9WU42	Mouse	PMID:10640276
Molecular Function	GO:0005515	protein binding	Hdac7	IPI	PR:O54946	Mouse	PMID:16260608
Molecular Function	GO:0019901	protein kinase binding	HDAC7	IPI	UniProtKB:P27448	Human	PMID:16980613
Molecular Function	GO:0019901	protein kinase binding	HDAC7	IPI	UniProtKB:Q7KZI7	Human	PMID:16980613
Molecular Function	GO:0005080	protein kinase C binding	HDAC7	IPI	UniProtKB:Q16512	Human	PMID:20188095
Molecular Function	GO:0033558	protein lysine deacetylase activity	HDAC7	IDA		Human	PMID:30538141
Molecular Function	GO:0003714	transcription corepressor activity	Hdac7	IDA		Mouse	PMID:10640276
Cellular Component	GO:0005737	cytoplasm	HDAC7	IDA		Human	PMID:16980613
Cellular Component	GO:0005737	cytoplasm	HDAC7	IDA		Human	PMID:17997710
Cellular Component	GO:0005829	cytosol	HDAC7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HDAC7	IDA		Human	PMID:16980613
Cellular Component	GO:0005634	nucleus	HDAC7	IDA		Human	PMID:17997710
Biological Process	GO:0007043	cell-cell junction assembly	Hdac7	IMP	MGI:MGI:3693627	Mouse	PMID:16873063
Biological Process	GO:0071260	cellular response to mechanical stimulus	Hdac7	IEP		Rat	PMID:19261284|RGD:9590196
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	hdac7a	IMP	ZFIN:ZDB-MRPHLNO-150225-3	Zfish	PMID:24240475
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Hdac7	IDA		Mouse	PMID:16260608
Biological Process	GO:0032703	negative regulation of interleukin-2 production	HDAC7	IDA		Human	PMID:17360565
Biological Process	GO:1901215	negative regulation of neuron death	Hdac7	IMP		Rat	PMID:21118817|RGD:9681718
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	HDAC7	IMP		Human	PMID:25411248
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	HDAC7	IMP		Human	PMID:17997710
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hdac7	IDA		Mouse	PMID:10640276
Biological Process	GO:0051402	neuron apoptotic process	Hdac7	IEP		Rat	PMID:21118817|RGD:9681718
Biological Process	GO:0030182	neuron differentiation	Hdac7	IEP		Rat	PMID:12850547|RGD:704464
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	HDAC7	IMP		Human	PMID:19351956
Biological Process	GO:0006476	protein deacetylation	HDAC7	IMP		Human	PMID:30538141
Biological Process	GO:0001570	vasculogenesis	Hdac7	IMP	MGI:MGI:3693627	Mouse	PMID:16873063

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern