Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HAVCR1
  • Mouse genes Havcr1
  • Rat genes Havcr1
  • Zfish genes havcr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Havcr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001786	phosphatidylserine binding	Havcr1	IDA		Mouse	PMID:18083575
Molecular Function	GO:0005515	protein binding	HAVCR1	IPI	UniProtKB:P0DTC2	Human	PMID:32995803
Molecular Function	GO:0005515	protein binding	HAVCR1	IPI	UniProtKB:P0DTC2	Human	PMID:33493263
Molecular Function	GO:0005515	protein binding	Havcr1	IPI	UniProtKB:Q6U7R4|UniProtKB:Q6U7R4	Mouse	MGI:MGI:6158812|PMID:15793576
Molecular Function	GO:0005515	protein binding	Havcr1	IPI	PR:Q3U497	Mouse	PMID:20566714
Molecular Function	GO:0001618	virus receptor activity	HAVCR1	IDA		Human	PMID:21536871
Cellular Component	GO:0016324	apical plasma membrane	Havcr1	IDA		Rat	PMID:16467126|RGD:7245980
Cellular Component	GO:0005903	brush border	Havcr1	IDA		Mouse	PMID:29402223
Cellular Component	GO:0009986	cell surface	Havcr1	IDA		Mouse	PMID:18083575
Cellular Component	GO:0009986	cell surface	Havcr1	IDA		Rat	PMID:19371613|RGD:2316593
Cellular Component	GO:0005737	cytoplasm	Havcr1	IDA		Rat	PMID:16467126|RGD:7245980
Cellular Component	GO:0005615	extracellular space	Havcr1	IDA		Rat	PMID:19522876|RGD:2316588
Cellular Component	GO:0005615	extracellular space	Havcr1	IDA		Rat	PMID:23552495|RGD:7244372
Cellular Component	GO:0031514	motile cilium	HAVCR1	IDA		Human	PMID:21536871
Cellular Component	GO:0045335	phagocytic vesicle	Havcr1	IDA		Rat	PMID:18414680|RGD:2316597
Biological Process	GO:0043277	apoptotic cell clearance	havcr1	IMP	ZFIN:ZDB-MRPHLNO-160413-1,ZFIN:ZDB-MRPHLNO-160413-2	Zfish	PMID:24898390
Biological Process	GO:0060097	cytoskeletal rearrangement involved in phagocytosis, engulfment	havcr1	IMP	ZFIN:ZDB-MRPHLNO-160413-1,ZFIN:ZDB-MRPHLNO-160413-2	Zfish	PMID:24898390
Biological Process	GO:0043652	engulfment of apoptotic cell	havcr1	IMP	ZFIN:ZDB-MRPHLNO-160413-1,ZFIN:ZDB-MRPHLNO-160413-2	Zfish	PMID:24898390
Biological Process	GO:0006911	phagocytosis, engulfment	Havcr1	IMP		Rat	PMID:18414680|RGD:2316597
Biological Process	GO:0033005	positive regulation of mast cell activation	Havcr1	IDA		Mouse	PMID:20566714
Biological Process	GO:0046677	response to antibiotic	Havcr1	IEP		Rat	PMID:19535489|RGD:2316586
Biological Process	GO:0032496	response to lipopolysaccharide	Havcr1	IDA		Mouse	PMID:29402223
Biological Process	GO:0010046	response to mycotoxin	Havcr1	IEP		Rat	PMID:18308701|RGD:2316503
Biological Process	GO:0007584	response to nutrient	Havcr1	IEP		Rat	PMID:18815216|RGD:2316595
Biological Process	GO:0033574	response to testosterone	Havcr1	IEP		Rat	PMID:23552495|RGD:7244372
Biological Process	GO:0009611	response to wounding	Havcr1	IMP		Mouse	PMID:29402223
Biological Process	GO:0009410	response to xenobiotic stimulus	Havcr1	IEP		Rat	PMID:19535489|RGD:2316586

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern