Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HAMP
  • Mouse genes Hamp
  • Rat genes Hamp
  • Zfish genes hamp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hamp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005507	copper ion binding	Hamp	IDA		Mouse	PMID:20113314
Molecular Function	GO:0001530	lipopolysaccharide binding	hamp	IDA		Zfish	PMID:24787654
Molecular Function	GO:0070891	lipoteichoic acid binding	hamp	IDA		Zfish	PMID:24787654
Molecular Function	GO:0042834	peptidoglycan binding	hamp	IDA		Zfish	PMID:24787654
Cellular Component	GO:0045179	apical cortex	Hamp	IDA		Rat	PMID:15684344|RGD:1599359
Cellular Component	GO:0005737	cytoplasm	Hamp	IDA		Rat	PMID:15684344|RGD:1599359
Cellular Component	GO:0005576	extracellular region	Hamp	IDA		Mouse	MGI:MGI:2137426|PMID:11447267
Cellular Component	GO:0005615	extracellular space	Hamp	IDA		Mouse	PMID:24357728
Cellular Component	GO:0005615	extracellular space	Hamp	IDA		Mouse	PMID:17435114
Cellular Component	GO:0005615	extracellular space	Hamp	IDA		Rat	PMID:24895335|RGD:11041618
Cellular Component	GO:0014704	intercalated disc	Hamp	IDA		Rat	PMID:17363462|RGD:11041718
Cellular Component	GO:0005634	nucleus	Hamp	IDA		Mouse	PMID:11113132
Biological Process	GO:0006953	acute-phase response	Hamp	IEP		Rat	PMID:22469696|RGD:8694421
Biological Process	GO:0007568	aging	Hamp	IEP		Rat	PMID:25318588|RGD:11041729
Biological Process	GO:0140367	antibacterial innate immune response	hamp	IDA		Zfish	PMID:28655927
Biological Process	GO:1903413	cellular response to bile acid	Hamp	IEP		Rat	PMID:19652645|RGD:11041639
Biological Process	GO:0071354	cellular response to interleukin-6	Hamp	IEP		Rat	PMID:23506423|RGD:11041627
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Hamp	IEP		Rat	PMID:23506423|RGD:11041627
Biological Process	GO:0071393	cellular response to progesterone stimulus	hamp	IMP	ZFIN:ZDB-MRPHLNO-160321-1	Zfish	PMID:26657863
Biological Process	GO:0071383	cellular response to steroid hormone stimulus	hamp	IMP	ZFIN:ZDB-MRPHLNO-160321-1	Zfish	PMID:26657863
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Hamp	IEP		Rat	PMID:23506423|RGD:11041627
Biological Process	GO:0071481	cellular response to X-ray	Hamp	IEP		Rat	PMID:17090718|RGD:11041722
Biological Process	GO:0042742	defense response to bacterium	Hamp	IDA		Mouse	PMID:11113131
Biological Process	GO:0042742	defense response to bacterium	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:23390527
Biological Process	GO:0050832	defense response to fungus	Hamp	IDA		Mouse	PMID:2995362
Biological Process	GO:0050829	defense response to Gram-negative bacterium	hamp	IDA		Zfish	PMID:24787654
Biological Process	GO:0050830	defense response to Gram-positive bacterium	hamp	IDA		Zfish	PMID:24787654
Biological Process	GO:0051649	establishment of localization in cell	Hamp	IGI	MGI:MGI:1315204	Mouse	PMID:21700773
Biological Process	GO:0006954	inflammatory response	Hamp	IGI	MGI:MGI:1201791	Mouse	PMID:20530874
Biological Process	GO:0006879	intracellular iron ion homeostasis	HAMP	IDA		Human	PMID:15514116
Biological Process	GO:0006879	intracellular iron ion homeostasis	Hamp	IDA		Mouse	MGI:MGI:2137426|PMID:11447267
Biological Process	GO:0006879	intracellular iron ion homeostasis	Hamp	IDA		Rat	PMID:14592944|RGD:1304454
Biological Process	GO:0034755	iron ion transmembrane transport	Hamp	IGI	MGI:MGI:1315204	Mouse	PMID:21700773
Biological Process	GO:0097421	liver regeneration	Hamp	IEP		Rat	PMID:22364558|RGD:8694419
Biological Process	GO:0042116	macrophage activation	Hamp	IMP		Mouse	PMID:22383698
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	HAMP	IMP		Human	PMID:12469120
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:23637785
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP		Mouse	PMID:24646470
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:24357728
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IDA		Mouse	PMID:20113314
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP	MGI:MGI:4351741	Mouse	PMID:24561287
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:16574947
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:22128145
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP		Mouse	PMID:20530874
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:20811044
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	hamp	IMP	ZFIN:ZDB-MRPHLNO-161021-1	Zfish	PMID:27233600
Biological Process	GO:0002262	myeloid cell homeostasis	Hamp	IMP	MGI:MGI:3701082	Mouse	PMID:24357729
Biological Process	GO:0045779	negative regulation of bone resorption	Hamp	IMP	MGI:MGI:4351741	Mouse	PMID:24561287
Biological Process	GO:0050728	negative regulation of inflammatory response	Hamp	IGI	MGI:MGI:1201791	Mouse	PMID:20530874
Biological Process	GO:1904479	negative regulation of intestinal absorption	HAMP	IMP		Human	PMID:12469120
Biological Process	GO:0034760	negative regulation of iron ion transmembrane transport	Hamp	IGI	MGI:MGI:1315204	Mouse	PMID:21700773
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Hamp	IMP		Mouse	MGI:MGI:3807465|PMID:18539898
Biological Process	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	Hamp	IMP		Rat	PMID:24424338|RGD:11041632
Biological Process	GO:0043032	positive regulation of macrophage activation	Hamp	IMP		Mouse	PMID:22383698
Biological Process	GO:0045732	positive regulation of protein catabolic process	Hamp	IDA		Mouse	PMID:21700773
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hamp	IGI	MGI:MGI:96629	Mouse	PMID:18800028
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hamp	IGI	MGI:MGI:103038	Mouse	PMID:18800028
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hamp	IGI	MGI:MGI:1315204	Mouse	PMID:18800028
Biological Process	GO:0030163	protein catabolic process	Hamp	IDA		Mouse	PMID:21700773
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	Hamp	IDA		Mouse	PMID:20530874
Biological Process	GO:0009617	response to bacterium	hamp	IDA		Zfish	PMID:16630661
Biological Process	GO:0036017	response to erythropoietin	Hamp	IEP		Rat	PMID:18306987|RGD:11041623
Biological Process	GO:0045471	response to ethanol	Hamp	IEP		Rat	PMID:19008338|RGD:11041624
Biological Process	GO:0010039	response to iron ion	HAMP	IMP		Human	PMID:12469120
Biological Process	GO:1990641	response to iron ion starvation	Hamp	IEP		Rat	PMID:21115976|RGD:11041626
Biological Process	GO:0033189	response to vitamin A	Hamp	IEP		Rat	PMID:24998947|RGD:11041625
Biological Process	GO:0010043	response to zinc ion	Hamp	IEP		Rat	PMID:21430246|RGD:11041613
Biological Process	GO:0006366	transcription by RNA polymerase II	Hamp	IGI	MGI:MGI:103038	Mouse	PMID:18800028
Biological Process	GO:0006366	transcription by RNA polymerase II	Hamp	IGI	MGI:MGI:96629	Mouse	PMID:18800028
Biological Process	GO:0006366	transcription by RNA polymerase II	Hamp	IGI	MGI:MGI:1315204	Mouse	PMID:18800028

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern