Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HADH
  • Mouse genes Hadh
  • Rat genes Hadh
  • Zfish genes hadh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hadh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	HADH	IDA		Human	PMID:11489939
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	Hadh	IDA		Mouse	PMID:15240869
Molecular Function	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity	Hadh	IMP		Rat	PMID:17491019|RGD:2302227
Molecular Function	GO:0042802	identical protein binding	HADH	IDA		Human	PMID:10231530
Molecular Function	GO:0070403	NAD+ binding	HADH	IDA		Human	PMID:10840044
Molecular Function	GO:0005515	protein binding	Hadh	IPI	UniProtKB:P26443	Mouse	MGI:MGI:4849622|PMID:20670938
Cellular Component	GO:0005737	cytoplasm	HADH	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005743	mitochondrial inner membrane	Hadh	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	HADH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Hadh	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Hadh	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Hadh	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005654	nucleoplasm	HADH	IDA		Human	GO_REF:0000052
Biological Process	GO:0006635	fatty acid beta-oxidation	HADH	IDA		Human	PMID:11489939
Biological Process	GO:0006635	fatty acid beta-oxidation	Hadh	IMP		Rat	PMID:17491019|RGD:2302227
Biological Process	GO:0046676	negative regulation of insulin secretion	Hadh	IMP		Rat	PMID:17491019|RGD:2302227
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Hadh	IMP		Mouse	MGI:MGI:5301049|PMID:21990309
Biological Process	GO:0050796	regulation of insulin secretion	Hadh	IMP		Mouse	MGI:MGI:4849622|PMID:20670938
Biological Process	GO:0014823	response to activity	Hadh	IDA		Rat	PMID:8231758|RGD:2302231
Biological Process	GO:0009725	response to hormone	Hadh	IEP		Rat	PMID:18191600|RGD:2302226
Biological Process	GO:0032868	response to insulin	Hadh	IEP		Rat	PMID:7050060|RGD:2302232
Biological Process	GO:0009410	response to xenobiotic stimulus	Hadh	IDA		Rat	PMID:12176671|RGD:1599883

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern