| GO term: | 3-hydroxyacyl-CoA dehydrogenase activity |
| Synonym: | 3-oxoacyl-thioester reductase activity |
| Synonym: | beta-hydroxyacylcoenzyme A dehydrogenase activity |
| Synonym: | beta-hydroxyacyl-coenzyme A synthetase activity |
| Synonym: | beta-hydroxyacyl dehydrogenase activity |
| Synonym: | beta-hydroxybutyrylcoenzyme A dehydrogenase activity |
| Synonym: | beta-ketoacyl-CoA reductase |
| Synonym: | beta-keto-reductase activity |
| Synonym: | L-3-hydroxyacyl CoA dehydrogenase activity |
| Synonym: | L-3-hydroxyacyl coenzyme A dehydrogenase activity |
| GO id: | GO:0003857 |
| Definition: | Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+). |
| Comments | See also 'long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509'. |
| Number of paths to term: | 1 |
denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship
molecular_functioncatalytic activityoxidoreductase activityoxidoreductase activity, acting on CH-OH group of donorsoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(+)-borneol dehydrogenase activity(+)-neomenthol dehydrogenase activity(+)-sabinol dehydrogenase activity(+)-trans-carveol dehydrogenase activity(-)-borneol dehydrogenase activity(-)-menthol dehydrogenase activity(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(R)-2-hydroxy-fatty acid dehydrogenase activity(R)-2-hydroxyacid dehydrogenase activity(R)-2-hydroxyisocaproate dehydrogenase activity(R)-3-hydroxyacid-ester dehydrogenase activity(R)-4-hydroxyphenyllactate dehydrogenase activity(R)-aminopropanol dehydrogenase activity(R,R)-butanediol dehydrogenase activity(S)-2-hydroxy-fatty acid dehydrogenase activity(S)-3-hydroxyacid-ester dehydrogenase activity(S)-carnitine 3-dehydrogenase activity(S)-usnate reductase activity(S,S)-butanediol dehydrogenase activity1,3-propanediol dehydrogenase activity1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity1,5-anhydro-D-fructose reductase activity1-deoxy-D-xylulose-5-phosphate reductoisomerase activity13-lipoxin reductase activity13-prostaglandin reductase activity15-hydroxyicosatetraenoate dehydrogenase activity15-hydroxyprostaglandin dehydrogenase (NAD+) activity15-hydroxyprostaglandin dehydrogenase (NADP+) activity15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity2,5-didehydrogluconate reductase activity2-(R)-hydroxypropyl-CoM dehydrogenase activity2-(S)-hydroxypropyl-CoM dehydrogenase activity2-alkyn-1-ol dehydrogenase activity2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity2-dehydropantoate 2-reductase activity2-dehydropantolactone reductase (A-specific) activity2-dehydropantolactone reductase (B-specific) activity2-deoxy-D-gluconate 3-dehydrogenase activity2-hydroxy-3-oxopropionate reductase activity2-hydroxymethylglutarate dehydrogenase activity2-hydroxytetrahydrofuran dehydrogenase activity2-oxoadipate reductase activity3''-deamino-3''-oxonicotianamine reductase activity3-(imidazol-5-yl)lactate dehydrogenase activity3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity3-alpha-hydroxycholanate dehydrogenase activity3-alpha-hydroxyglycyrrhetinate dehydrogenase activity3-dehydro-L-gulonate 2-dehydrogenase activity3-dehydrosphinganine reductase activity3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity3-hydroxyacyl-CoA dehydrogenase activity [GO:0003857] (8 genes, 10 annotations)3-hydroxybenzyl-alcohol dehydrogenase activity3-hydroxybutyrate dehydrogenase activity3-hydroxybutyryl-CoA dehydrogenase activity3-hydroxyisobutyrate dehydrogenase activity3-hydroxymenthone dehydrogenase activity3-hydroxypimeloyl-CoA dehydrogenase activity3-hydroxypropionate dehydrogenase (NAD+) activity3-hydroxypropionate dehydrogenase (NADP+) activity3-isopropylmalate dehydrogenase activity3-keto sterol reductase activity3-ketoglucose-reductase activity3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity3beta-hydroxy-5alpha-steroid dehydrogenase activity3beta-hydroxy-5beta-steroid dehydrogenase activity4-(hydroxymethyl)benzenesulfonate dehydrogenase activity4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity4-hydroxybutyrate dehydrogenase activity4-hydroxycyclohexanecarboxylate dehydrogenase activity4-hydroxythreonine-4-phosphate dehydrogenase activity4-oxoproline reductase activity4-phosphoerythronate dehydrogenase activity5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity5-amino-6-(5-phosphoribosylamino)uracil reductase activity5-exo-hydroxycamphor dehydrogenase activity5-hydroxyvalerate dehydrogenase activity6-endo-hydroxycineole dehydrogenase activity6-hydroxyhexanoate dehydrogenase activity6-pyruvoyltetrahydropterin 2'-reductase activity8-oxocoformycin reductase activityacetoacetyl-CoA reductase activityacetoin dehydrogenase activity +acylglycerone-phosphate reductase activityalcohol dehydrogenase (NAD) activity +alcohol dehydrogenase [NAD(P)+] activity +aldo-keto reductase (NADP) activity +aldose 1-dehydrogenase activityaldose-6-phosphate reductase (NADPH) activityallyl-alcohol dehydrogenase activityapiose 1-reductase activityaryl-alcohol dehydrogenase (NAD+) activityaryl-alcohol dehydrogenase (NADP+) activitybenzyl-2-methyl-hydroxybutyrate dehydrogenase activityC-3 sterol dehydrogenase (C-4 sterol decarboxylase) activitycarbonyl reductase (NADPH) activitycarnitine 3-dehydrogenase activitycarveol dehydrogenase activitychlordecone reductase activitychlorophyll(ide) b reductase activitycholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activitycholestanetetraol 26-dehydrogenase activitycinnamyl-alcohol dehydrogenase activitycodeinone reductase (NADPH) activityconiferyl-alcohol dehydrogenase activitycyclohexane-1,2-diol dehydrogenase activitycyclohexanol dehydrogenase activitycyclopentanol dehydrogenase activityD-arabinitol 2-dehydrogenase activityD-arabinitol 4-dehydrogenase activityD-arabinitol dehydrogenase, D-ribulose forming (NADP+) activityD-arabinitol dehydrogenase, D-xylulose forming (NADP+) activityD-arabinose 1-dehydrogenase (NAD) activityD-arabinose 1-dehydrogenase [NAD(P)+] activityD-iditol 2-dehydrogenase activityD-lactate dehydrogenase activityD-malate dehydrogenase (decarboxylating) activityD-pinitol dehydrogenase activityD-threo-aldose 1-dehydrogenase activityD-xylose 1-dehydrogenase (NAD) activityD-xylose 1-dehydrogenase (NADP+) activityD-xylulose reductase activitydiethyl 2-methyl-3-oxosuccinate reductase activitydihydrobunolol dehydrogenase activitydihydrokaempferol 4-reductase activitydiiodophenylpyruvate reductase activitydimethylmalate dehydrogenase activitydTDP-4-dehydro-6-deoxyglucose reductase activitydTDP-4-dehydrorhamnose reductase activitydTDP-6-deoxy-L-talose 4-dehydrogenase activitydTDP-galactose 6-dehydrogenase activityepoxide dehydrogenase activityerythrulose reductase activityfarnesol dehydrogenase activityflavanone 4-reductase activityfluoren-9-ol dehydrogenase activityfructose 5-dehydrogenase (NADP+) activityfructuronate reductase activitygalactitol 2-dehydrogenase activitygalactitol-1-phosphate 5-dehydrogenase activitygalactose 1-dehydrogenase (NADP+) activitygalactose 1-dehydrogenase activityGDP-4-dehydro-6-deoxy-D-mannose reductase activityGDP-4-dehydro-D-rhamnose reductase activityGDP-6-deoxy-D-talose 4-dehydrogenase activityGDP-L-fucose synthase activityGDP-mannose 6-dehydrogenase activitygeraniol dehydrogenase activitygluconate dehydrogenase activity +glucose 1-dehydrogenase (NAD+) activityglucose 1-dehydrogenase (NADP+) activityglucose 1-dehydrogenase [NAD(P)] activityglucose-6-phosphate dehydrogenase activityglucuronolactone reductase activityglycerate dehydrogenase activityglycerol 2-dehydrogenase (NADP+) activityglycerol dehydrogenase [NAD(P)+] activityglycerol dehydrogenase [NAD+] activityglycerol dehydrogenase [NADP+] activityglycerol-1-phosphate dehydrogenase [NAD(P)+] activityglycerol-3-phosphate 1-dehydrogenase [NADP+] activityglycerol-3-phosphate dehydrogenase [NAD(P)+] activityglycerol-3-phosphate dehydrogenase [NAD+] activityglyoxylate reductase (NADP) activityglyoxylate reductase activityhexadecanol dehydrogenase activityhistidinol dehydrogenase activityhomoisocitrate dehydrogenase activityhomoserine dehydrogenase activityhydroxycyclohexanecarboxylate dehydrogenase activityhydroxymalonate dehydrogenase activityhydroxymethylfurfural reductase (NADH) activityhydroxymethylfurfural reductase (NADPH) activityhydroxymethylfurfural reductase activityhydroxymethylglutaryl-CoA reductase (NADPH) activityhydroxymethylglutaryl-CoA reductase activityhydroxyphenylpyruvate reductase activityhydroxypyruvate reductase activityIMP dehydrogenase activityindanol dehydrogenase activityindole-3-acetaldehyde reductase (NADH) activityindole-3-acetaldehyde reductase (NADPH) activityindolelactate dehydrogenase activityisocitrate dehydrogenase activity +isocitrate-homoisocitrate dehydrogenase activityisopiperitenol dehydrogenase activityisopropanol dehydrogenase (NADP+) activityketol-acid reductoisomerase activityL-arabinitol 2-dehydrogenase activityL-arabinitol 4-dehydrogenase activityL-arabinose 1-dehydrogenase (NAD+) activityL-arabinose 1-dehydrogenase (NADP+) activityL-glucuronate reductase activityL-glycol dehydrogenase activityL-gulonate 3-dehydrogenase activityL-iditol 2-dehydrogenase activityL-idonate 5-dehydrogenase activityL-lactate dehydrogenase activityL-malate dehydrogenase activityL-rhamnose 1-dehydrogenase activityL-threonate 3-dehydrogenase activityL-threonine 3-dehydrogenase activityL-xylose 1-dehydrogenase activityL-xylulose reductase (NAD+) activityL-xylulose reductase (NADP+) activitylactaldehyde reductase (NADPH) activitylactaldehyde reductase activity +long-chain-3-hydroxyacyl-CoA dehydrogenase activitylong-chain-alcohol dehydrogenase activitymalate dehydrogenase (decarboxylating) activitymalate dehydrogenase (NADP+) activitymalate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activitymalate dehydrogenase (oxaloacetate-decarboxylating) activitymannitol 2-dehydrogenase (NADP+) activitymannitol 2-dehydrogenase activitymannitol dehydrogenase activitymannitol-1-phosphate 5-dehydrogenase activitymannose-6-phosphate 6-reductase activitymannuronate reductase activitymethanol dehydrogenase activitymethylglyoxal reductase (NADH-dependent) activitymethylglyoxal reductase (NADPH-dependent) activitymethylglyoxal reductase (NADPH-dependent, acetol producing)mevaldate reductase activity +morphine 6-dehydrogenase activityN-acetylhexosamine 1-dehydrogenase activityN-acylmannosamine 1-dehydrogenase activityoctanol dehydrogenase activityomega-hydroxydecanoate dehydrogenase activityoxaloglycolate reductase (decarboxylating) activitypantoate 4-dehydrogenase activityperillyl-alcohol dehydrogenase activityphenylcoumaran benzylic ether reductase activityphosphogluconate 2-dehydrogenase activityphosphogluconate dehydrogenase (decarboxylating) activityphosphoglycerate dehydrogenase activitypropanediol-phosphate dehydrogenase activityprostaglandin D2 11-ketoreductase activityprostaglandin H2 endoperoxidase reductase activityprostaglandin-E2 9-reductase activityprostaglandin-F synthase activitypterocarpin synthase activitypyridoxal 4-dehydrogenase activityquinate 3-dehydrogenase (NAD+) activityquinate 3-dehydrogenase (NADP+) activityretinol dehydrogenase activityribitol 2-dehydrogenase activityribitol-5-phosphate 2-dehydrogenase activityribose 1-dehydrogenase (NADP+) activityS-(hydroxymethyl)glutathione dehydrogenase activitysalutaridine reductase (NADPH) activitysepiapterin reductase activitysequoyitol dehydrogenase activityserine 3-dehydrogenase activityshikimate 3-dehydrogenase (NAD+) activityshikimate 3-dehydrogenase (NADP+) activitysinapyl alcohol dehydrogenase activitysorbitol-6-phosphate 2-dehydrogenase activitysorbose 5-dehydrogenase (NADP+) activitysorbose reductase activitysteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor +sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activitysulcatone reductase activitytagaturonate reductase activitytartrate dehydrogenase activitytetrahydroxynaphthalene reductase activitytropine dehydrogenase activitytropinone reductase activityUDP-4-keto-rhamnose-4-keto-reductase activityUDP-glucose 6-dehydrogenase activityUDP-N-acetylglucosamine 6-dehydrogenase activityUDP-N-acetylmuramate dehydrogenase activityureidoglycolate dehydrogenase activityuronate dehydrogenase activityvellosimine dehydrogenase activityvery long-chain-3-hydroxyacyl-CoA dehydrogenase activityvomifoliol 4'-dehydrogenase activityMouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc |
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last database update 06/05/2013 MGI 5.13 |
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